Gujoo Ofloxacin Tablet

Adult dosage

○ The usual adult dosage is 300～600 mg of ofloxacin daily in 2～3 divided doses. ○ For Hansen's disease, take 400～600 mg of this medicine daily in 2～3 divided doses. In principle, use it in combination with other anti-Hansen's disease medicines. Adjust the dosage appropriately according to age and symptoms.

This medication is a fluoroquinolone antibiotic used for the treatment of certain bacterial infections. However, it can cause serious side effects such as tendinitis or tendon rupture, peripheral neuropathy, central nervous system disorders, and exacerbation of myasthenia gravis, thus caution is advised. If such serious adverse reactions occur, discontinuation of this medication is required, and other drugs in the same category should not be used. In patients with myasthenia gravis, administration can worsen symptoms, so this medication is contraindicated. This drug is only used for specific infections such as acute bacterial sinusitis, acute exacerbation of chronic bronchitis, simple urinary tract infections, and acute otitis media when no other treatment options are available. Elderly patients, those with impaired kidney function, solid organ transplant recipients, and corticosteroid users are at increased risk for tendon rupture, so concurrent use with corticosteroids should be avoided. In the presence of symptoms of tendinitis or tendon rupture, avoid exercise and immediately discontinue this medication. Additionally, this medication can exacerbate neuromuscular blocking effects in patients with myasthenia gravis, so caution is necessary. This medication is not to be administered to patients with hypersensitivity to it or with a history of tendinitis or tendon rupture, individuals under 18 years of age, pregnant women or those who may become pregnant, breastfeeding women, individuals with certain genetic deficiencies, and patients with epilepsy. It should be administered with caution in patients with severe renal impairment, elderly people, a history of mental illness, liver impairment, or those with aortic aneurysms or cardiac valve abnormalities. This medication has the potential to cause serious allergic reactions such as anaphylaxis; if unusual symptoms occur, discontinue the medication immediately and consult a healthcare provider. Various side effects have been reported affecting the kidneys, liver, gastrointestinal, hematologic, neuropsychiatric, skin, musculoskeletal, respiratory, circulatory, and urogenital systems, necessitating periodic evaluations. In particular, neuropsychiatric side effects can manifest as insomnia, dizziness, seizures, and hallucinations; notify your physician immediately if such symptoms arise. This medication should be protected from excessive exposure to sunlight or artificial ultraviolet light, and if photosensitivity reactions are suspected, discontinue use immediately. Diabetic patients requiring blood glucose control should be vigilant for signs of hypoglycemia or hyperglycemia and check blood sugar levels frequently. This medication interacts with many other drugs, so it is crucial to inform your healthcare provider about any other medications you are taking, especially when using anticoagulants, certain anti-inflammatory drugs, antidiabetic medications, antacids, etc. Pregnant and nursing women should not take this medication, and breastfeeding should be discontinued if it is necessary to take it. Safety has not been established for use in children and adolescents who are still growing. Elderly patients may experience increased drug concentrations due to decreased renal function, necessitating dose adjustments and caution. In cases of overdose, symptoms such as drowsiness, dizziness, and facial swelling can occur, requiring prompt medical assistance. When administered intravenously, it should be given slowly and should not be mixed with specific solutions.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, worsening of myasthenia gravis, anaphylactic shock, anaphylactic reactions, rash, itching, erythema, edema, fever, warmth sensation, blisters, erythema, phototoxic reaction, hematuria, acute renal failure, renal stones, interstitial nephritis, increased BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, increased ALP, elevated gamma-GTP, increased total bilirubin, cholestatic jaundice, fulminant hepatitis, membranous colitis, bloody stools, abdominal pain, diarrhea, nausea, vomiting, gastric and abdominal discomfort, cirrhosis, anorexia, gastric abdominal pain, dyspepsia, chest pain, thirst, taste abnormalities, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, reduced hematocrit level, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechial and purpuric hemorrhage, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, neurotension, sleep disturbances, confusion, anxiety, depression, restlessness, euphoric feelings, delusions, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory and vestibular sensory disorders, ataxia, aphasia, heaviness in the head, skin and mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, arthralgia, myalgia, muscle weakness, myositis, fatigue, elevated CPK, increased myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, nosebleed, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, storage urination, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vulvovaginal candidiasis, increased vaginal discharge, itching of the female genital region, menstrual irregularities, uterine cramps, genital rashes in females, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, malaise, fever, aortic aneurysm, aortic dissection, heart valve regurgitation, heart valve insufficiency, drowsiness, nausea, facial flushing, facial edema, numbness, inaccurate speech, loss of direction sense

This medication should be stored in a tightly closed container to prevent air and moisture ingress. This will help maintain the drug's efficacy and prevent degradation.

Appearance

Round film-coated tablet, white to pale yellowish

Package unit

Company packaging unit