Zynal Tablet (Naproxen Sodium)

Key information summary

Efficacy & effects

This medication is used for the treatment of degenerative joint diseases such as rheumatoid arthritis and osteoarthritis, ankylosing spondylitis, tendinitis, acute gout, and dysmenorrhea. It is also effective in relieving various musculoskeletal pains due to bursitis and skeletal muscle disorders, such as sprains, bruises, trauma, and low back pain. Additionally, it helps alleviate postoperative pain, migraines, and pain after tooth extraction, thereby reducing discomfort for patients. Overall, this drug is conveniently used to treat various inflammatory and painful conditions.

Dosage

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis Administer 275-550mg of sodium naproxen for adults orally, twice daily (every 12 hours). 2. Acute gout Administer 825mg of sodium naproxen as the initial dose for adults orally, then 275mg every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis Adults.

Precautions

Caution is required when this medication is taken by individuals who regularly consume three or more alcoholic beverages daily, as it may increase the risk of gastrointestinal bleeding; consultation with a doctor or pharmacist is essential. This medication may increase the risk of serious thrombotic events such as myocardial infarction or stroke in individuals with cardiovascular issues or risk factors. There is a possibility of ulceration or bleeding in the gastrointestinal tract, requiring close monitoring of symptoms, especially in the elderly or those with a history of gastrointestinal diseases. Patients with peptic ulcers, severe blood abnormalities, significantly impaired liver or kidney function, severe hypertension, or hypersensitivity to this drug's components should not take it. Patients with a history of peptic ulcers, blood abnormalities, liver and kidney diseases, hypertension, or asthma should be cautious while taking this medication. This medication may cause various side effects, such as allergic reactions, gastrointestinal bleeding, liver or kidney dysfunction, skin rashes, headaches, dizziness, etc., so if any abnormal symptoms occur, discontinuation should be immediate, and a doctor should be consulted. Long-term use requires regular blood tests and liver function tests to check for abnormalities, and dosages and duration should be kept to a minimum wherever possible. Taking this medication alongside other non-steroidal anti-inflammatory drugs (NSAIDs) or specific medications might increase the risk of side effects, so inform your physician of any other medications being taken. Especially in late pregnancy, it may pose risks to the fetus, so it should be avoided, and breastfeeding women are also advised not to take this medication. The safety of this medication has not been established for infants and children, particularly those under 2 years of age, so its use is not recommended. Elderly patients should start at a low dose and use caution due to an increased risk of gastrointestinal bleeding and other side effects. Overdose may cause symptoms such as drowsiness, indigestion, and vomiting; in such cases, immediate medical attention is necessary. This medication should be stored out of reach of children and should not be transferred to other containers.

Side effects

Hives, severe swelling (edema), cold sweat, difficulty breathing, hematemesis, gastrointestinal bleeding, peptic ulcer, perforation, agranulocytosis, eosinophilia, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia, platelet dysfunction, jaundice, hepatitis, renal impairment, glomerulonephritis, hematuria, hyperkalemia, interstitial nephritis, nephrotic syndrome, renal failure, aseptic meningitis, severe headache, altered consciousness, Stevens-Johnson syndrome, epidermolysis bullosa,

Interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs (NSAIDs) or high-dose methotrexate used in chemotherapy.

Alternatives / Same-ingredient medications

• 

  Anaprox Tablets (Naproxen Sodium)

  Same ingredient
• 

  Anax Tablet (Naproxen Sodium)

  Same ingredient
• 

  Alasaxen Tablet (Naproxen Sodium)

  Same ingredient
• 

  Poxen Tablet 275 milligrams (Naproxen Sodium)

  Same ingredient

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