Donghwa Ofloxacin Tablet

Adult dose

The usual adult dose is 300～600 mg of ofloxacin per day, taken in 2～3 divided doses. For Hansen's disease, take 400～600 mg of this medicine per day in 2～3 divided doses. In principle, use it in combination with other anti-Hansen's disease medicines. The dose may be adjusted appropriately according to age and symptoms.

This drug may cause serious side effects such as tendinitis or tendon rupture, peripheral neuropathy, and central nervous system disturbance symptoms, so caution is needed. In particular, patients with myasthenia gravis should not use this drug as it may worsen their symptoms. Furthermore, it is limited to use for acute bacterial infection treatment and should only be administered when no other treatment options are available. This drug should be avoided in combination with corticosteroids to minimize the risk of tendon rupture, particularly in elderly patients, those with impaired renal function, and organ transplant recipients. If symptoms of pain, inflammation, or tendon rupture occur, the medication should be stopped immediately, and rest should be taken while avoiding physical activity. Patients with myasthenia gravis should be especially cautious due to neuromuscular blocking action that may worsen symptoms. Those with hypersensitivity or a history of tendinitis or tendon rupture, growing children and adolescents, pregnant and nursing women, and patients with certain genetic disorders should not use this drug. Caution should be exercised in patients with severe renal impairment, the elderly, those with mental disorders, liver dysfunction, and a history of aortic disease. During treatment, allergic reactions, hypersensitivity, liver and renal dysfunction, gastrointestinal issues, blood abnormalities, neurological issues, skin issues, musculoskeletal issues, and respiratory and circulatory adverse reactions may occur, so if any abnormal symptoms arise, consult a physician immediately. This drug may react sensitively to ultraviolet light, so sun exposure or artificial UV exposure should be avoided, and if symptoms like rash appear, treatment should be discontinued. Additionally, there is a risk of seizures, thus caution is advised for patients with epilepsy or central nervous system disorders. Regular liver and renal function tests and blood tests should be conducted during the treatment period, and adequate hydration is necessary. This drug may cause neurological issues like dizziness, so caution is needed while driving or operating machinery. Diabetic patients managing blood sugar must closely monitor for symptoms of hypoglycemia or hyperglycemia, and check for interactions with concurrent medications such as anticoagulants, anti-inflammatory drugs, and certain antacids. Women who are pregnant or may become pregnant, as well as nursing women, should not use this drug and should discontinue breastfeeding. This drug's safety has not been established for growing children and adolescents, so it should not be administered. Elderly patients should be administered cautiously, adjusting doses and dosing intervals due to potential increased drug concentration from renal impairment. In case of overdose, symptoms such as drowsiness, nausea, and dizziness may occur, requiring careful observation and sufficient hydration. When administering intravenously, it should be injected slowly and should not be administered with certain solutions. Lastly, this drug must be stored out of reach of children, and transferring it to other containers should be avoided.

• Tendinitis
• tendon rupture
• peripheral neuropathy
• central nervous system effects
• exacerbation of myasthenia gravis
• anaphylactic shock
• anaphylactoid reaction
• rash
• itching
• erythema

This drug should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White to off-white round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle