Tamadol Injection (Tramadol Hydrochloride)

Key information summary

Efficacy & effects

This medication is used to relieve severe and moderate acute and chronic pain, such as pain caused by various types of cancer and pain occurring after diagnosis or surgery.

Dosage

As tramadol hydrochloride, 50-100mg is administered via intravenous or intramuscular injection, repeated as necessary every 4-5 hours. A maximum of 400mg can be administered per day.

Precautions

Caution is required as this medication can cause seizures if the recommended dosage is exceeded. Patients at risk of seizures or those with epilepsy should use it cautiously only when necessary. Long-term use of this medication can lead to psychological and physical dependence, so it should be administered under strict supervision for patients at risk of drug abuse. When taken with central nervous system depressants or alcohol, severe sedation, respiratory depression, and coma may occur, so it should be used with extreme caution in such cases. Patients with specific genetic characteristics that metabolize the drug faster are at increased risk of respiratory depression and require dose adjustment and monitoring. It should not be administered to children under 12 or adolescents under 18 who have undergone tonsillectomy and adenoidectomy, and even when necessary in this age group, extreme caution should be exercised. The ampoule injection should be handled carefully as glass fragments may be mixed in when breaking the container, particularly when administering to children or the elderly. This medication should not be administered to patients with acute alcohol intoxication, central nervous system drug intoxication, severe respiratory depression, head injury patients, patients taking MAO inhibitors, patients with severe renal or hepatic impairment, pregnant or breastfeeding women, and patients with specific allergies. Furthermore, it should be administered with caution to patients taking morphine, those with biliary diseases, liver impairment, alcohol abuse, renal impairment, those taking central nervous system depressants, and a history of seizures. Drowsiness, dizziness, and other symptoms may occur during administration, so driving or operating dangerous machinery should be avoided, and caution is needed in assessing conditions in patients with acute abdominal diseases. In case of overdose, severe respiratory depression and seizures may occur, necessitating immediate emergency treatment, and naloxone can be used as an antidote. This medication interacts with various drugs, so it is essential to consult with a specialist when used in combination with other medications, especially central nervous system depressants, MAO inhibitors, and antidepressants. It is safer not to use this medication during pregnancy or breastfeeding, as it may transmit to the infant through breast milk and pose a risk. Older patients may have increased blood concentration, so dosage should be limited, and it is advisable not to exceed 300mg per day for those over 75 years old. Patients receiving this medication should fully discuss treatment goals and discontinuation plans with their healthcare providers and carefully monitor for dependence and abuse risks.

Side effects

Seizures, severe allergic reactions (shock, anaphylaxis, hives, bronchospasm, angioedema), respiratory depression, difficulty breathing, exacerbation of asthma, cough and fever accompanied by respiratory issues, liver abnormalities (elevated liver enzyme levels, jaundice symptoms), severe skin reactions (Stevens-Johnson syndrome), serious neurological symptoms (confusion, seizures, severe headaches, vision abnormalities, paralysis, fainting), severe swelling and urination abnormalities (generalized edema

Alternatives / Same-ingredient medications

• Tridol Injection 50 milligrams (Tramadol Hydrochloride)

  Same ingredient
• 

  Tridol Capsules 50 mg (Tramadol Hydrochloride)

  Same ingredient
• Hanol Tramadol Hydrochloride Injection

  Same ingredient
• Doranjin Injection 50mg (Tramadol Hydrochloride)

  Same ingredient

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