Boryeong Duricep Dry Syrup 125 mg/5 mL (Cefadroxil Hydrate)

Adult dose

1) For urinary tract infections: For uncomplicated lower urinary tract infections (such as cystitis), administer 1-2 g (potency) divided into 1-2 oral doses per day. For other urinary tract infections, administer 2 g (potency) divided into 2 doses daily. 2) For skin and soft tissue infections: 1 g (potency) divided into 1-2 oral doses per day. 3) For pharyngitis and tonsillitis: For beta-hemolytic streptococcal infections leading to pharyngitis or tonsillitis, administer 1 g (potency) divided into 1-2 doses orally for 10 days.

Child dose

1) For urinary tract infections and skin and soft tissue infections: 30 mg/kg (potency) divided into 2 oral doses per day. 2) For pharyngitis and tonsillitis: 30 mg/kg (potency) divided into 1-2 oral doses per day.

This drug should not be administered to certain patients. For example, patients who have previously experienced shock from this medication or who are allergic to cephalosporin antibiotics should not use it. Additionally, it should not be given to patients with infectious mononucleosis or those with genetic disorders that prevent lactose digestion. There are also patients who should be cautious while using this drug. Those with a history of hypersensitivity reactions or allergic to penicillin antibiotics, individuals with allergic constitutions, or severe kidney disease patients should use it with particular caution. Elderly patients or those with gastrointestinal disorders should monitor their condition closely while taking this medication, as should individuals allergic to the pigments included in this medication. This drug may rarely cause serious side effects. Symptoms such as shock, severe allergic reactions, abnormal blood conditions, liver or kidney dysfunction, and gastrointestinal issues may occur, so if any abnormal symptoms arise, it is essential to discontinue use immediately and consult healthcare professionals. Severe skin reactions like a significant rash or Stevens-Johnson syndrome may also occur, so careful observation is necessary. To prevent the occurrence of resistant bacteria, it is advisable to take this medication only for the minimum duration after susceptibility testing has been performed. If hypersensitivity is suspected, dosing should be stopped immediately, and appropriate treatment should be initiated. Long-term use may require regular blood, kidney, and liver function tests, and dosage adjustments may be necessary for patients with decreased kidney function. When used with other drugs that may affect the kidneys, this medication may increase the risk of kidney dysfunction, so caution is advised during concomitant use. Additionally, it may increase the plasma concentration of this medication when taken with certain other drugs. Women who are pregnant or may become pregnant should carefully consider the benefits and risks of using this medication, and nursing mothers should also use it with caution. Elderly patients are at an increased risk of side effects due to decreased bodily functions, so dosage and administration intervals should be adjusted while monitoring their condition closely. This drug can impact the results of some clinical tests, so this information should be conveyed to healthcare professionals prior to testing. Lastly, this medication may cause photosensitivity reactions, so it is advisable to avoid exposure to sunlight.

Serious side effects

Urticaria, shock, anaphylaxis, severe edema accompanied by increased blood pressure, chest tightness, difficulty breathing, dyspnea, asthma attacks, seizures, confusion, visual disturbances, paralysis, acute renal failure, severe colitis including pseudomembranous colitis, Stevens-Johnson syndrome, severe allergic reactions, severe skin abnormal reactions, serious neurological symptoms, severe edema or urinary abnormalities

Mild side effects

• Rash
• erythema
• facial swelling
• angioedema
• mucosal vesicles
• itching
• fever
• thrombocytopenia
• agranulocytosis
• eosinophilia

This drug is sensitive to light; therefore, it should be stored in a place that is not exposed to light. It should be kept at room temperature in a tightly sealed container to prevent air or moisture ingress.

Appearance

It is a white to grayish-white powder.

Package unit

261.1 g (with solvent added 470 mL)