Cimet Tablets 300 mg (Cimetidine)

Adult dose

As cimetidine, take 400 mg orally twice a day (morning and bedtime) or administer 800 mg orally once a day (at bedtime). In addition, take 300 mg orally four times a day (after meals and at bedtime). The dose can be increased to a total of 1.6 g with 400 mg orally four times a day (after meals and at bedtime). For acute gastritis and acute exacerbations of chronic gastritis, administer 200 mg orally twice a day or 400 mg once a day.

Child dose

Administered orally in divided doses of 20-40 mg per kg of body weight per day.

This medication may contain glass fragments when using glass ampule injections, so it should be handled with caution, especially when administered to children or the elderly. It should not be used in patients with allergic reactions or hypersensitivity to this drug, those at risk for certain cardiac arrhythmias, and patients with hereditary lactose intolerance. Patients with renal or liver impairment, the elderly, children under 19 years of age, or those undergoing hemodialysis may require dose adjustments or modifications in dosing intervals, and administration should be performed only after confirming the malignancy due to the possibility of concealing symptoms of gastric cancer. Various adverse reactions may occur during the administration of this drug, such as leukopenia, liver dysfunction, renal dysfunction, allergic reactions, dyspepsia, neurological abnormalities, and skin rashes, so if symptoms occur, immediate consultation with a physician is required. It is advisable to administer at the lowest effective dose while observing therapeutic effects, and if no effect is seen, consider switching to other treatment methods. Particularly, the elderly or those with chronic diseases may have an increased risk of pneumonia, so caution is necessary. There are many interactions with other medications, so dose adjustments or discontinuation may be required depending on the types of concurrent medications. Pregnant or lactating women should decide cautiously on the use of this medication considering the potential effects on the fetus or newborn, and it is recommended to discontinue breastfeeding during treatment. In case of overdose, serious side effects such as respiratory depression may occur, and immediate emergency treatment is necessary. When administered as an injection, rapid intravenous infusion may cause arrhythmias or hypotension, so it should be infused slowly. Store in a safe place out of reach of children, and transferring the medication to another container may cause quality degradation or accidents, so it should be avoided.

Serious side effects

• General malaise, weakness, subcutaneous bleeding, mucosal bleeding, fever → immediate discontinuation of medication and treatment if blood tests are needed.
• Jaundice, hepatitis, increased AST, ALT → liver abnormalities.
• Fever, renal dysfunction (increased BUN, creatinine) → renal abnormalities.
• Shock, anaphylactic reaction, systemic rash, respiratory distress → severe allergic reactions.
• Consciousness disorder, convulsions, agitation, psychosis, depression, excitement, hallucinations, disorientation → severe neurological symptoms.

Mild side effects

• Leukopenia
• agranulocytosis
• aplastic anemia
• thrombocytopenia
• pancytopenia
• aplastic anemia
• hepatitis
• increased AST
• ALT
• liver fibrosis

This medication may be sensitive to air and light, so it should be stored in a tightly closed container. Doing so can help maintain the drug's efficacy for a longer time.

Appearance

Beige tablets

Package unit

500 tablets/bottle