Posiel Tablet 5mg (Dapagliflozin Propane Diol Hydrate)

Adult dose

This medication can be taken once daily at any time, regardless of food. The tablet should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years have not been established.

This medication should not be used in certain patients. Patients allergic to the main ingredient or additives, those with type 1 diabetes or diabetic ketoacidosis, should avoid this medication due to potential risks. Moreover, it contains anhydrous lactose, making it unsuitable for patients with genetic conditions such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption. Patients undergoing dialysis should also not use this medication. Patients with reduced fluid volume or kidney function issues should use this medication cautiously. It can lower blood pressure or temporarily worsen kidney function; therefore, elderly patients or those taking diuretics must be especially careful. Before starting this medication, evaluate fluid status and kidney function, and after administration, continuously monitor for symptoms of low blood pressure and kidney function. Patients with moderate to severe kidney impairment may experience reduced blood sugar control effectiveness. Common side effects of this medication include genital infections and urinary tract infections. Women and patients with a history of infections should be particularly cautious as the risk of reinfection may be higher. Hypoglycemia symptoms may occur, particularly if taken with insulin or sulfonylureas, increasing the risk of hypoglycemia. Symptoms of reduced fluid volume or dehydration have also been reported, so it is important to consult medical professionals immediately if dehydration symptoms occur. Rarely, serious metabolic disturbances like diabetic ketoacidosis may develop, requiring immediate medical attention if symptoms like nausea, vomiting, abdominal pain, or breathing difficulties occur. Additionally, symptoms such as pain, swelling, or redness in the perineum indicate a serious infection like perineal necrosis, necessitating immediate treatment. This medication is not recommended for patients with severely impaired liver function. Elderly patients, those with low blood pressure, or patients on diuretics must be particularly cautious of blood pressure drops and reduced fluid volume. It is safest for pregnant or breastfeeding women to avoid this medication, and the safety and efficacy in children have not yet been established. This medication can interact with other drugs, so especially when taken with diuretics, insulin, or sulfonylureas, dosage adjustments may be necessary. In case of overdose, there are no specific antidotes; treatment should be symptomatic, following medical guidance. During the use of this medication, closely monitor for symptoms of hypoglycemia and infection, and consult medical staff immediately if any abnormal symptoms arise. Finally, it is important to keep this medication out of the reach of children and store it in its original container to maintain quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, consciousness disturbance, vision changes, paralysis, urinary problems

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infection, fungal infection, hypoglycemia, dry mouth, dizziness, constipation, back pain, painful urination, polyuria, nocturia, increased hematocrit, decreased renal creatinine clearance at the beginning of treatment, dyslipidemia, elevated serum creatinine at the beginning of treatment, increased blood urea, weight loss, chest pain, asthenia, pain, swelling, foreign body sensation, facial swelling, facial pain, warmth, flu-like symptoms

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. It is best to store it at room temperature between 1°C and 30°C.

Appearance

Yellow, film-coated, round tablets that are biconvex on both sides

Package unit

28 tablets/PTP [14 tablets/PTP x 2]