Medication info
Acephen Tablets

Acephen Tablets

OTC medicationTablet경구
Ingredient · strength
Acetaminophen›100mg / 1 tabletAnhydrous Caffeine›15mg / 1 tabletEphedrine Hydrochloride›11mg / 1 tablet
Manufacturer / importer
(주)엘앤씨바이오
Appearance
White round tablet
Packaging
60 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 202204455 · Notified 2022.12.09

Summary

Main use
Relief of cold symptoms (sore throat, cough, etc.)
Who takes it
Adults
Adult dose
For adults aged 15 years and older, take 2 tablets at a time, 3 times a day, 30 minutes after meals.

Ingredients

Manufacturer
(주)엘앤씨바이오

Efficacy & effects

Relief of cold symptoms (sore throat, cough, etc.)

  • Sore throat
  • cough
  • phlegm
  • chills
  • fever
  • headache
  • joint pain
  • muscle pain
View approved original text

This medicine is used to relieve various symptoms of cold such as sore throat, cough, phlegm, chills, fever, headache, joint pain, and muscle pain.

How to take

Adult dose

For adults aged 15 years and older, take 2 tablets at a time, 3 times a day, 30 minutes after meals.

Precautions

This medication can put strain on the liver, so those who consume alcohol above a certain amount daily should consult a doctor or pharmacist before taking it. Although rare, the ingredients in this medication can cause serious skin rashes or blisters and allergic reactions; if such symptoms occur, stop taking the medication immediately and consult a specialist. Be careful not to exceed the maximum daily dosage of this medication and do not take it with other medications containing the same ingredients. Particularly, the ingredients can cause acute skin reactions, so if fever or abnormal skin symptoms appear, discontinue use and consult a specialist. Those with an allergic constitution or a history of hypersensitivity to specific components, infants under 3 months, or those taking certain antidepressants should not take this medication. During treatment, it is safest not to take cough medications, other cold medications, antipyretics, sedatives, or antihistamines together with this medication. Children or individuals with certain diseases, as well as pregnant or breastfeeding women, must consult a specialist before use. If symptoms such as rash, vomiting, dizziness, or insomnia appear while taking this medication, stop immediately and consult a specialist. In particular, if respiratory distress, severe skin symptoms, or liver dysfunction symptoms appear, immediate medical attention is necessary. In children, it is generally not recommended for those under 2 years old, and if necessary, a doctor's review is required. Ensure to adhere to the prescribed dosage and regimen and avoid prolonged use, as well as abstain from alcohol while taking this medication. Caution is advised when taking this medication with certain antibiotics or other drugs due to the risk of side effects. Store in a place out of reach of children, protect from direct sunlight, and keep in a cool and dry place. Additionally, it is important not to transfer to another container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

  • Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor → severe allergic reaction.
  • Severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa → severe skin adverse reaction.
  • Asthma, cough with fever, dyspnea or difficulty breathing → respiratory issues.
  • Skin or eyes turn yellow (jaundice), extreme lethargy → liver issues (jaundice).
  • Severe headache, seizures, altered consciousness.

Mild side effects

Rash, redness (flushing), itching, nausea, vomiting, loss of appetite, constipation, edema (swelling), dizziness, anxiety, tremors, insomnia, high anion gap metabolic acidosis (HAGMA)

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not take this medication with MAO inhibitors (antidepressants, antipsychotics, mood stabilizers, anti-Parkinson's drugs, etc.), cough suppressants, other cold medications, antipyretics, sedatives, or antihistamines. Do not take this medication within 2 weeks of stopping MAO inhibitors. If taking medications for diabetes, gout, arthritis, anticoagulants, steroids, or others, consult a doctor.

Storage

This medication should be stored in a sealed container to prevent air exposure and kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents degradation.

Appearance and packaging

Appearance

White round tablet

Package unit

60 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QI feel tightness in my chest and cold sweat after taking it.

    Symptoms such as hives, chest tightness, cold sweat, and difficulty breathing may occur rarely after taking the medication, which are described as shock symptoms in the instructions. Immediately stop taking it and consult a doctor or pharmacist; if symptoms are severe, seek emergency care.

    Answers 1 · 2026.09.14

  • QThis is a medication for cold symptoms; can I take it before meals?

    The usage instructions state that for individuals aged 15 and older, the dosage is 2 tablets three times a day after meals, 30 minutes after eating. Please follow the specified schedule, and do not take it together with other cold medications or antipyretics.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.