Rabemore Tablet 10/500mg (Rabeprazole Sodium, Sodium Bicarbonate)

Adult dose

1. Gastric ulcer, duodenal ulcer: Ordinarily administered orally to adults once daily at 10/500mg. Depending on symptoms, may administer 20/500mg orally once daily. Typically, for gastric ulcers, it is administered up to 8 weeks, and for duodenal ulcers, up to 6 weeks. 2. Erosive or ulcerative gastroesophageal reflux disease: Administer 10/500mg or 20/500mg orally once daily for 4 to 8 weeks. If proton pump inhibitors (PPIs) do not treat after 8 weeks, an additional 8 weeks of 10/500mg or 20/500mg can be taken orally twice per day. However, administering 20/500mg twice a day is only for patients confirmed with severe mucosal damage. 3. Relief of symptoms of gastroesophageal reflux disease: Administer 10/500mg once daily. If symptoms are not controlled after 4 weeks, further medical attention is needed. After symptoms disappear, on-demand therapy with 10/500mg once daily can be used to control subsequent symptoms as necessary. 4. Long-term maintenance for gastroesophageal reflux disease: Administer 10/500mg or 20/500mg orally once a day depending on the patient. 2. Patients with liver impairment: Adverse reactions linked to hepatic encephalopathy have been reported in patients with liver cirrhosis. Therefore, it should be used with caution. 3. Elderly patients: Caution is warranted as hepatic function may be impaired. 4. Pediatrics: Safety in children has not been established.

Child dose

Safety in children has not been established.

This medication should not be used in certain patients. Individuals with allergies or hypersensitivity to this medication or its components, those taking Atazanavir or Rilpivirine, and pregnant or breastfeeding women should not take this medication. Patients with liver or kidney dysfunction, elderly patients, those with weakened heart or lung function, patients with electrolyte imbalances, and patients who need to limit sodium intake should use this medication with caution. This medication contains a dye called Yellow No. 5, which requires caution in individuals allergic to this component. When taking this medication, allergic symptoms such as skin rash, urticaria, or itching may occur, and if such symptoms appear, the use should be stopped immediately. Regular blood tests may be necessary as red blood cell or white blood cell counts can change. It may affect liver function, resulting in elevated liver enzymes or symptoms of hepatitis and jaundice, so periodic checks on liver health are essential. Cardiac issues or blood pressure abnormalities, headaches, dizziness, and other neurological symptoms have also been reported, along with gastrointestinal symptoms like diarrhea, constipation, abdominal pain, nausea, and vomiting. Respiratory symptoms such as coughing or breathing difficulties may emerge, and in rare cases, severe lung disorders can occur; if there are symptoms of fever, cough, or breathing difficulty, immediate consultation with healthcare personnel is advised. Muscle pain or joint pain, skin rashes, hair loss, and visual disturbances have also been reported, so these symptoms should be carefully monitored. This medication suppresses gastric acid secretion, and long-term use may increase the risk of bone fractures and may lead to vitamin B12 absorption impairment. Additionally, there may be a slight increase in the risk of gastrointestinal infections, so if diarrhea persists, inform healthcare personnel. Caution is advised when driving or operating machinery as drowsiness may occur. There may be interactions with other drugs, so it is essential to inform healthcare personnel if taking especially Warfarin, Methotrexate, Atazanavir, or Rilpivirine. It is safer not to use this medication during pregnancy or while breastfeeding. Elderly individuals may have impaired liver function, so if any unusual symptoms occur, the use should be stopped immediately, and a doctor should be consulted. This medication should be swallowed whole without chewing or crushing, and stored out of reach of children.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities associated with cough and fever, yellowing of skin or eyes (jaundice), generalized lethargy, liver abnormalities, sudden and very severe headaches, thunderclap headaches, seizures, confusion of consciousness

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechial hemorrhage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. This helps to preserve the effectiveness and safety of the medication for a longer time.

Appearance

Bright yellow-brown oval film-coated tablet

Package unit

28 tablets/bottle