Sitagliptin 100 mg Tablets (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. For renal impairment patients, dose adjustment is needed based on renal function. - For mild to moderate renal impairment (glomerular filtration rate 45 to less than 90), no dose adjustment is needed. - For glomerular filtration rate 30 to less than 45, administer 50 mg once daily. - For glomerular filtration rate 15 to less than 30

This medication may cause allergic reactions; if symptoms such as rash, hives, or difficulty breathing occur, discontinue use immediately and consult a doctor. While taking this medication, serious pancreatitis can occur; therefore, if experiencing abdominal pain, vomiting, or persistent abdominal discomfort, inform healthcare professionals immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication, and those with allergies to this medication or its ingredients should also avoid it. Patients with impaired kidney function need to adjust the dosage of this medication, so it is important to discuss with a doctor to determine the appropriate dosage if there are kidney diseases. During treatment with this medication, signs of hypoglycemia may occur, especially when used in conjunction with insulin or sulfonylureas, so caution is advised. If severe joint pain or skin rash occurs, immediately discontinue use and seek medical attention from a specialist. Women who are pregnant or breastfeeding are not recommended to use this medication, and its safety in children under 18 years has not been established. Elderly patients are at higher risk of kidney function decline, thus regular kidney function tests before and after administration are important. In case of overdose, seek appropriate medical treatment immediately, and this remedy can be partially removed through hemodialysis. This medication may interact with other antihyperglycemic agents; therefore, inform your doctor or pharmacist of any other medications you are taking.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe allergic reactions, severe rash, blisters, skin peeling, Stevens-Johnson syndrome, exfoliative skin conditions, pancreatitis (including acute pancreatitis), difficulty breathing, acute renal failure, severe edema, severe and disabling joint pain, bullous pemphigoid, liver abnormalities (elevated liver enzymes, potential jaundice), thrombocytopenia, rhabdomyolysis, pneumonia, cardiac arrest, severe

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• constipation
• vomiting
• headache
• muscle pain
• limb pain
• back pain
• itching
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent exposure to air. It is recommended to store it at room temperature between 1 and 30 degrees Celsius. Proper storage can prolong the effectiveness of the medication.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle