Medication info

Cough EN-ES Syrup

OTC medicationSyrup경구
Ingredient · strength
Dextromethorphan Hydrobromide Hydrate›75mg / 100mLDL-Methylephedrine Hydrochloride›131.25mg / 100mLChlorpheniramine Maleate›15mg / 100mLAmmonium Chloride›1g / 100mL
Manufacturer / importer
(주)제뉴파마
Appearance
Light reddish syrup
Packaging
20mL/pack x 20
Approval status
Active

MFDS item code 202005018 · Notified 2020.07.13

Summary

Main use
Relief of cough and phlegm
Who takes it
Adults · Children
Adult dose
20 mL per dose, taken 3-4 times a day after meals and at bedtime.
Child dose
Ages 11 to under 15: 13 mL per dose, Ages 8 to under 11: 10 mL per dose, Ages 5 to under 8: 7 mL per dose, Ages 3 to under 5: 5 mL per dose, 2 years and under

Ingredients

Manufacturer
(주)제뉴파마

Efficacy & effects

Relief of cough and phlegm

  • Cough
  • phlegm
View approved original text

This medication is used to improve respiratory symptoms such as cough and phlegm.

How to take

Adult dose

20 mL per dose, taken 3-4 times a day after meals and at bedtime.

Child dose

Ages 11 to under 15: 13 mL per dose, Ages 8 to under 11: 10 mL per dose, Ages 5 to under 8: 7 mL per dose, Ages 3 to under 5: 5 mL per dose, 2 years and under

Precautions

This medication should not be taken by anyone who has an allergy to this medication or any of its ingredients or who has experienced hypersensitivity reactions. Additionally, individuals currently taking or having ceased taking certain antidepressants or antipsychotics known as MAO inhibitors within the last two weeks should not take this medication. Infants under 3 months of age should not take this medication in syrup form, and children under 15 years of age should not take this medication in tablet form. While taking this medication, do not use other cold medications, expectorants, antihistamines, sedatives, or alcohol. When taking this medication, it is advised to avoid alcohol, and since drowsiness may occur, it is recommended to refrain from operating vehicles or machinery. If an infant under 2 years of age needs to take this medication, a doctor's consultation is mandatory. Individuals with a history of allergic reactions such as rashes, fever, or itching should consult a doctor or pharmacist before taking this medication. Those with chronic diseases such as liver, kidney, thyroid disorders, or diabetes, patients with high fever, heart disease, hypertension, elderly individuals, and women who are pregnant or breastfeeding should consult a healthcare professional before using this medication. Individuals with glaucoma or urinary disorders, patients under medical treatment, and those with specific cough symptoms (e.g., asthma, chronic bronchitis, cough lasting more than a week) must also consult before taking this medication. If symptoms such as rash, vomiting, dizziness, urinary difficulty, anxiety, shaking, or insomnia occur during medication use, or if symptoms do not improve after 5-6 doses, stop taking the medication immediately and consult a healthcare professional. The prescribed dosage and administration should be strictly followed, and when administering to children, guardians should provide guidance and supervision. This medication should be stored out of reach of children and in a cool place away from direct sunlight and moisture. Additionally, to maintain quality, do not transfer to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives

Mild side effects

  • Rash
  • redness
  • itching
  • nausea
  • vomiting
  • loss of appetite
  • dizziness
  • urinary difficulty
  • dry mouth
  • anxiety
Show 2 more
  • tremors
  • insomnia

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not take this medication with MAO inhibitors (antidepressants, antipsychotics, mood stabilizers, Parkinson's medications, etc.), other expectorants, cold medications, antihistamines, or sedatives.

Food interactions

Do not consume alcohol during the course of this medication.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

Light reddish syrup

Package unit

20mL/pack x 20

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QHow much should I give to my four-year-old child?

    According to the instructions, children aged 3 years to under 5 years should take 5 mL three to four times a day after meals and at bedtime. It should not be given to children under 2 years of age, so if the child is taking other cold medications or if you have concerns, please ask a pharmacist first.

    Answers 1 · 2026.09.14

  • QIs it acceptable to have a can of beer while taking cough medicine?

    You are advised not to take this medication with alcohol and to avoid drinking while taking it. Symptoms such as dizziness may occur, so please refrain from alcohol during the course of treatment, even in small amounts.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.