Donepezil Tablets 5 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, the dosage is 5 mg once daily taken before bedtime. Administer 5 mg for 4-6 weeks and evaluate the clinical response before increasing to 10 mg. When increasing to 10 mg daily, caution should be taken regarding gastrointestinal adverse reactions. Underweight female patients aged 85 and older should not exceed 5 mg per day and require careful monitoring.

Child dose

There is no experience with the use in pediatric patients.

This medication is used in the treatment of symptoms of Alzheimer's type dementia, with Donepezil Hydrochloride Hydrate as the active ingredient. This medication should not be used in certain patients. For example, individuals with allergies to this medication or any of its components, women who are pregnant or may become pregnant, and breastfeeding women should not take this medication. In addition, as this medication contains lactose, patients with lactose intolerance or certain genetic metabolic disorders should also avoid its use. Patients with heart disease or a history of gastrointestinal diseases should take special care when using this medication. It may slow the heart rate or cause arrhythmias and may increase the risk of exacerbating peptic ulcers. Patients with asthma or obstructive pulmonary disease may also experience worsening symptoms when taking this medication, so it should be used cautiously. This medication can cause various side effects, and in rare cases, severe heart problems, gastrointestinal bleeding, liver dysfunction, and seizures may occur. Commonly reported mild side effects include nausea, vomiting, diarrhea, dizziness, and insomnia. If side effects are severe or unusual symptoms occur, immediate consultation with medical personnel is necessary. This medication has not been approved for use in other types of dementia or memory disorders other than Alzheimer's type dementia and should only be taken under the diagnosis and supervision of a specialist. During treatment, it is necessary to regularly monitor the heart condition, and particular caution is required in patients with a history of heart disease. This medication may affect driving or operation of machinery, so caution is needed, especially at the beginning of treatment or when the dosage is changed. Women who are pregnant or breastfeeding should generally not use this medication; if necessary, a decision should be made after consultation with medical personnel. Safety in pediatric patients has not been established, so it should not be used in children. This medication is metabolized in the liver, so patients with liver function abnormalities should be cautious, and potential interactions with other medications should be disclosed if the patient is taking other drugs. In cases of overdose, dangerous symptoms such as severe nausea, vomiting, hypotension, and respiratory depression may occur, necessitating immediate hospitalization, where atropine may be used as an antidote. When storing this medication, keep it in a tightly closed container to prevent exposure to air or moisture, and it is best to keep it at room temperature between 1°C and 30°C.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe drowsiness throughout the body, sudden and extremely severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, decreased urination, etc.

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• fever
• dizziness
• insomnia
• drowsiness

This medication should be stored in a tightly closed container to prevent air or moisture exposure. Additionally, it is advisable to store it at room temperature between 1°C and 30°C.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle