Akrab Tablet 60/10 mg

Adult dose

This medication is taken once daily with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosage for Pimasartan is 30-60 mg once daily, taken regardless of meals, and can be increased to 120 mg once daily if blood pressure is not controlled. The antihypertensive effect typically appears within two weeks of initiation, with maximum effectiveness observed around 8 to 12 weeks.

This medication may cause serious harm or death to the fetus and newborn if taken during pregnancy, especially during the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. This medicine should not be used in patients with severe liver dysfunction or active liver disease, nor in patients with muscle disorders. Pregnant women, women who may become pregnant, and nursing mothers should not take this medication. It should not be administered to patients undergoing dialysis, patients with moderate to severe liver impairment, or obstructive biliary disease. Patients with allergies to the ingredients or certain hereditary conditions like lactose intolerance should avoid taking this medicine. Patients with a history of alcoholism or liver disease, impaired kidney function, elderly patients, or patients with reduced blood volume or sodium require special caution when taking this medication. Common side effects during use can include muscle pain, muscle weakness, fatigue, headache, dizziness, dyspepsia, vomiting, abnormal liver function, and other symptoms. If any abnormal symptoms occur, consult a doctor immediately. This medication has hypotensive effects, so symptoms of low blood pressure may appear, particularly at the start of treatment or when the dose is increased; careful monitoring of blood pressure and kidney function is necessary. There may be interactions with specific medications during use, so inform your doctor or pharmacist about any other medications being taken. The safety of this medication in children has not been established, and it should not be given to children under 10 years old. Elderly patients may have increased exposure to this medication, which may require dosage adjustment, and caution is particularly advised regarding muscle-related side effects. This medication should not be given to patients with moderate to severe liver dysfunction, and if symptoms of liver dysfunction appear, treatment should be discontinued immediately. In the case of overdose, symptoms such as hypotension, palpitations, and bradycardia may occur, thus requiring appropriate treatment based on symptoms. This medication should be kept out of reach of children and stored in its original container to prevent misuse or deterioration of product quality.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, difficulty breathing, asthma attacks, cough with fever accompanied respiratory abnormalities, yellowing of skin or eyes (jaundice), severe systemic malaise, sudden and severe headaches, lightning headaches, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

Headache, dizziness, syncope, sedation, migraine, dyspepsia, vomiting, nausea, upper abdominal pain, asthenia, foreign body sensation, increased serum creatine phosphokinase (CPK), abnormal liver enzyme levels, increased ALT, elevated serum lactate dehydrogenase (LDH), increased liver enzyme levels, hypokalemia, fatigue, edema, myalgia, hypertension, ventricular extrasystole, pruritus, localized urticaria, facial flushing, hot flashes, erectile dysfunction, muscle

This medicine is sensitive to air and moisture, so it must be stored in a tight container. Additionally, avoid storing in excessively hot or cold places, ideally at a room temperature between 1 to 30 degrees Celsius.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP*3]