Ceftriaxone Injection 2g (Ceftriaxone Sodium Hydrate)

Adult administration

Adults and children over 12 years: Administer 1-2g once daily by intravenous or intramuscular injection as ceftriaxone. For infections caused by severe pathogens or pathogens showing moderate sensitivity, the dose may be increased to 4g once daily. For treatment of gonorrhea, a single intramuscular injection of 250mg is recommended. For the prevention of infections before and after surgery, a single dose of 1-2g should be administered 30 to 90 minutes prior to surgery.

Child administration

Newborns (within 14 days of birth): Administer 20-50mg per Kg body weight once daily, not exceeding 50mg. Infants and children (from 15 days to 12 years): Administer 20

This medication must not be mixed or injected simultaneously with solutions containing calcium. Especially, it should not be administered to newborns due to the risk of precipitation when calcium combines with this drug. Patients who are allergic to this drug or its components or have had hypersensitivity reactions to cephalosporins or penicillin antibiotics should not use this medication. Furthermore, caution is required for those with allergies to certain local anesthetics. Patients with severe kidney disease or allergic tendencies should use this medication carefully, adjusting the dose or increasing the administration interval as necessary. Use of this medication may lead to side effects such as diarrhea, rash, abnormal liver function, and decreased blood cell counts, therefore, if abnormal symptoms occur, patients must inform medical staff immediately. Rarely, severe allergic reactions, neurological abnormalities, hepatitis, and decreased kidney function may occur, so the patient's condition should be continuously monitored while receiving treatment. This medication should be administered cautiously to pregnant or nursing women, and particularly, it should not be given to newborns and premature infants due to the risk of bilirubin encephalopathy. Regular liver and kidney function tests and blood tests are recommended during treatment. Since there is no specific antidote for overdose, symptomatic treatment is necessary. Dizziness and other side effects may occur during driving or operating machinery, so caution is advised. There may be interactions with other drugs; patients must disclose any medications they are taking, especially avoiding simultaneous use with calcium supplements or certain antibiotics. During storage, use the medication as soon as possible after preparation and avoid using calcium-containing solutions for dilution.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, high fever with severe rash, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanying cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and very severe headache, lightning headache, seizures, consciousness

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• dizziness
• bronchospasm
• loose stools
• nausea

This medication must be stored in a sealed container to prevent air or moisture from entering. Additionally, it is important to maintain a room temperature of 1 to 30 degrees Celsius when storing the medication. This helps preserve the effectiveness and prevents deterioration.

Appearance

A white to light yellow crystalline powder filled in a colorless, transparent vial

Package unit

10 vials/box [1 vial x 10]