LAPES Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: Typically, adults should take 10 mg of rabeprazole sodium orally once a day. Depending on symptoms, it may be increased to 20 mg orally once a day. Treatment duration is up to 8 weeks for gastric ulcer and up to 6 weeks for duodenal ulcer. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg should be taken orally once a day for 4 to 8 weeks. If symptoms do not improve, it may be increased to 10 mg or 20 mg orally twice a day for an additional 8 weeks. Note that 20 mg twice a day is for patients with confirmed severe mucosal damage. For symptom relief of gastroesophageal reflux disease: 10 mg should be taken orally once a day. If symptoms are not controlled after 4 weeks, further medical consultation is required. Once symptoms resolve, on-demand therapy using 10 mg once a day can be used to control any recurring symptoms. For long-term maintenance therapy of gastroesophageal reflux disease: Depending on the patient, 10 mg or 20 mg should be taken orally once a day. For Helicobacter pylori eradication: Patients infected with Helicobacter pylori should undergo eradication therapy. This medicine should be administered in combination with clarithromycin 500 mg and amoxicillin 1 g, taken orally twice a day for 7 days. For Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg orally once a day. The dose can be adjusted up to 120 mg per day based on individual patient needs. A dose of up to 100 mg can be taken once a day, while a dose of 120 mg should be taken as 60 mg twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to 1 year. ◯ For patients with hepatic impairment: Abnormal reactions of hepatic encephalopathy have been reported in patients with liver cirrhosis, so use should be approached cautiously. ◯ For children: Safety has not been established in pediatric patients. ◯ For the elderly: Caution is advised due to frequent liver function impairment.

This medicine should not be used in patients with a history of allergic reactions to this drug or its components. Particular caution is required for patients allergic to penicillin or macrolide antibiotics, and when used in combination with certain antibiotics. Pregnant or breastfeeding women should not use this medicine. Patients with poor liver function or the elderly should use this medicine cautiously, and caution is needed if there is a history of allergies. If any allergic symptoms such as rash, hives, or itching occur while on this medication, discontinue use immediately. Regular blood tests and liver function tests are important to check for abnormalities. This medicine may cause various side effects in multiple areas such as the heart, gastrointestinal tract, nervous system, respiratory system, muscles, and skin, so consult a medical professional immediately if symptoms occur. Long-term use may increase the risk of osteoporosis and fractures, so caution is advised. Long-term use of this medicine may lower serum magnesium levels, so it is necessary to periodically check magnesium levels if needed. Suppressing gastric acid secretion may slightly increase the risk of bacterial infections in the stomach, so consult a doctor if diarrhea persists. Caution is advised when driving or operating machinery as dizziness or drowsiness may occur. There may be interactions with other medications, so be sure to inform healthcare professionals of any medications being taken. Caution is especially needed when used in conjunction with antiviral medications, antibiotics, and anticoagulants. This medicine should not be chewed or crushed but swallowed whole, and it should be stored out of reach of children. Pregnant or breastfeeding individuals should not use this medicine, and the elderly should use it cautiously due to increased risk of side effects from decreased liver function. The safety in children has not been established, so its use in pediatric patients is not recommended. In case of overdose, there is no specific antidote, and appropriate treatment should be given according to symptoms.

Serious side effects

Urticaria, tightness in the chest, difficulty breathing, bloody stools, fulminant hepatitis, liver dysfunction, jaundice, serious allergic reactions, severe skin reactions, respiratory issues, liver issues (jaundice), severe neurological symptoms, severe swelling or urination abnormalities, toxic epidermal necrolysis (Lyell's syndrome), Stevens-Johnson syndrome, interstitial pneumonia, acute interstitial nephritis, coma, anaphylaxis, angioedema, hypomagnesemia

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• purpura

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the effectiveness of the medication and prevent deterioration.

Appearance

Pale yellow round enteric-coated tablet

Package unit

Inner packaging - 28 tablets/box [14 tablets/Alu Alu pack * 2]