Donepezil 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, it is administered once daily at 5 mg before bedtime. The 5 mg dose should be administered for 4 to 6 weeks, and after clinical response assessment, it may be increased to 10 mg. When increasing to 10 mg daily, caution is necessary for gastrointestinal adverse reactions. Underweight female patients aged 85 and older should not exceed 5 mg daily and require careful monitoring.

Child dose

There is no experience in using this medication in children.

This medication should not be used by women who are allergic to any specific ingredients, are pregnant, or are breastfeeding. Patients with genetic lactose-related disorders should avoid taking this medication. Patients with heart disease or a history of peptic ulcers should exercise caution while taking this medication, and medical observation is needed as symptoms may worsen. Patients with asthma or obstructive pulmonary disease should use this medication cautiously as it may worsen symptoms. Patients with extrapyramidal disorders such as Parkinson's disease may experience aggravated symptoms from this medication. This medication contains specific pigments, so patients who are allergic should exercise caution. During use, serious side effects such as fainting, cardiac problems, gastrointestinal bleeding, liver dysfunction, seizures, and movement disorders may occur, and if any adverse symptoms arise, consult a doctor immediately. Common side effects may include nausea, vomiting, diarrhea, dizziness, insomnia, headache, fatigue, and drowsiness. This medication is used for the treatment of Alzheimer's type dementia, and its therapeutic effects should be regularly evaluated; if ineffective, discontinuation should be considered. Patients with heart disease may experience arrhythmias, and an electrocardiogram may be necessary. This medication may increase gastric acid secretion, which can worsen peptic ulcers, so patients with a history of gastrointestinal disease should be cautious. Dizziness or fatigue may occur while driving or operating machinery, so caution is advised. Pregnant or breastfeeding women should refrain from using this medication; if necessary, consultation with a specialist is advised. Safety in children has not been established, so it should not be used in that group. There may be interactions with other medications, so inform your doctor or pharmacist about any medications you are taking. In cases of overdose, serious symptoms such as nausea, vomiting, bradycardia, hypotension, and respiratory depression may occur; immediate medical attention is required. Store this medication out of reach of children, and do not transfer it to different containers for safety.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcers, perforation of the duodenum, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures (epilepsy, convulsions), intracerebral hemorrhage, cerebrovascular accidents, extrapyramidal disorders (motor dysfunction, ataxia, movement disorders, dystonia, tremors, involuntary movements, gait disturbance, abnormal posture, speech disorders), neuroleptic malignant syndrome (stupor, extreme rigidity)

Mild side effects

Nausea, vomiting, dizziness, diarrhea, insomnia, abdominal pain, loss of appetite, headache, fatigue, drowsiness, sweating, skin rash, aggressive behavior, tremors, gait disturbance, involuntary movements, decreased concentration, mental dullness, lethargy, thrombocytopenia, anemia, urinary incontinence, frequent urination, urinary retention, pain, toothache, malaise, flushing, edema (including facial edema), fever, decreased body temperature, hematological abnormalities (decreased hematocrit, leukopenia)

This medication should be kept in a sealed container to prevent exposure to air or moisture and stored at a temperature between 1 to 30 degrees Celsius at room temperature. Storing it this way will help maintain the drug's effectiveness.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle