Starova Tablet 5 mg (Rosuvastatin Calcium)

Adult dosage

Administer 5 mg once daily at any time of day without regard to meals. The maintenance dose can be adjusted as needed, generally to 10 mg once daily. Maintenance doses should be adjusted appropriately based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with a maximum increase to 20 mg once daily.

Children's dosage

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, administer a dose of 5 mg to 20 mg once daily. The dosage should be adjusted according to the individual therapy goals of each patient.

This medication should not be used in certain patients. For instance, it should not be administered to patients with an allergy to any of its components, severely impaired liver function, muscle disorders, or significantly reduced kidney function. Women who are pregnant or breastfeeding, as well as women who may become pregnant, must utilize appropriate contraception to reduce pregnancy risk before using this medication, and caution is advised due to potential risks to the fetus. Patients at high risk of muscle-related disorders, such as those with moderately to severely impaired kidney function, reduced thyroid function, a family history of muscle disorders, previous muscle toxicity, alcoholics, and individuals of Asian descent, should avoid high doses of this medication or use it carefully. This medication contains lactose, so patients with lactose intolerance or related genetic conditions should not take it. It is essential to undergo regular liver function tests and muscle function tests while taking this medication. Particular caution is warranted for patients with a history of liver disease or those consuming alcohol excessively; any symptoms such as muscle pain, weakness, or cramps should be reported to healthcare professionals immediately. Furthermore, this medication can interact with other drugs, so patients should inform their healthcare providers of any concomitant medications. The combination with certain drugs may increase the blood concentration of this medication, raising the risk of muscle disorders. Pregnant or breastfeeding patients should not use this medication, and those planning to become pregnant should consult before use. In case of overdose, since there is no specific antidote, symptomatic treatment and monitoring of liver and muscle function is required. Finally, this medication may cause side effects such as dizziness, so caution is advised while driving or operating machinery.

Serious side effects

Allergic reactions including urticaria and angioedema, chest tightness, breathing difficulties, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, polyneuropathy, severe muscle weakness, ocular myasthenia, acute kidney injury, oliguria, worsening of renal failure due to acute critical condition, rhabdomyolysis, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• diarrhea
• hematuria

Store this medication in a tightly sealed container to protect it from air and moisture. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/box [30 tablets (15 tablets/PTP (AluAlu) × 2)]