Crown Tablet 10 mg (Rosuvastatin Calcium)

Adult dosage

Patients with primary hypercholesterolemia, mixed dyslipidemia, primary dysbetalipoproteinemia, and homozygous familial hypercholesterolemia are administered the initial dose of 5 mg once daily at any time regardless of meals. If necessary, the dose can be adjusted at intervals of 4 weeks or more to maintain a dose of 10 mg once daily, with a maximum dose of 20 mg once daily.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is administered once daily in the range of 5 mg to 20 mg. The dosage should be adjusted according to each patient's treatment goal at intervals of 4 weeks or more.

This medication should not be used in certain patients. For instance, it should not be administered to patients who are allergic to it, those with active liver disease, those with muscle disorders, patients with severe renal impairment, pregnant or breastfeeding women, and women of childbearing age who are not using appropriate contraception. This medication may affect liver function; patients with a history of liver disease or excessive alcohol intake should have regular liver function tests. Additionally, if symptoms of muscle pain or weakness occur, they should consult a physician immediately, and in severe cases, they may need to discontinue the medication. While taking this medication, there may be interactions with other drugs, so any medications being taken must be disclosed to healthcare providers. In particular, the risk of muscle-related side effects may increase when used in combination with certain antiviral agents, immunosuppressants, and fibrate drugs. Pregnant or breastfeeding women should not take this medication, and women who can become pregnant should employ adequate contraception methods. If pregnancy is confirmed, the medication should be stopped immediately. In case of overdose, there is no specific antidote, and management should be based on symptoms along with liver function and muscle enzyme tests. This medication may rarely cause serious skin reactions, liver damage, kidney abnormalities, or neurological issues, so patients should consult healthcare providers immediately if unusual symptoms occur. Also, caution is advised while driving or operating machinery as dizziness may occur during the use of this medication.

Serious side effects

Allergic reactions including hives and angioedema, chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, acute renal failure, oliguria, rhabdomyolysis, severe muscle weakness, severe skin reactions, immune-mediated necrotizing myopathy, severe edema, dyspnea, cough, thrombocytopenia, polyneuropathy, peripheral neuropathy, interstitial lung disease.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• thrombocytopenia
• diarrhea

Store this medication in a tightly closed container to protect it from air and moisture, at temperatures between 1 and 30 degrees Celsius. Proper storage can prolong the effectiveness of the medication.

Appearance

Pink round film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP X 2]