Rosuvastatin Calcium 10 mg Tablets

Adult dosage

The initial dose is 5 milligrams once daily, and if a greater reduction in LDL cholesterol is required, it can be adjusted to a maintenance dose. The maintenance dose is usually 10 milligrams once daily, and most patients are managed at this dose. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response every 4 weeks or longer, with a maximum daily increase of up to 20 milligrams as needed.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17 years) is 5 to 20 milligrams once daily. The dosage should be adjusted according to the treatment goals recommended for each individual patient.

This medication should not be used in certain patients. For example, patients with an allergy to this medication's components, with active liver disease, with muscle disorders, those with severe impairment of certain kidney functions, women who are pregnant or breastfeeding, and fertile women not using adequate contraception should not take this medication. Furthermore, this medication should be used with caution in patients at high risk of muscle injury. Elderly patients, those with hypothyroidism, patients with mild impairment of kidney function, alcohol abusers, and those with a history of certain genetic muscle disorders should consult with a physician before taking this medication. During treatment with this medication, regular liver function tests should be done, and any symptoms such as muscle pain, muscle weakness, or muscle cramps should be reported to healthcare professionals immediately. Additionally, severe muscle injury or rhabdomyolysis can occur, and if symptoms are severe, the medication should be discontinued. This medication may interact with other drugs, so it is crucial to inform healthcare professionals about any other medications being taken. In particular, the risk of muscle injury may increase when used in combination with certain antibiotics, antifungals, immunosuppressants, and fibrate medications. Pregnant or breastfeeding women should not use this medication, and fertile women should use proper contraception before taking this medication. In cases of overdose, there is no specific antidote, so one should visit a medical institution immediately for proper treatment, and liver function and muscle enzyme levels should be monitored regularly. Lastly, this medication may cause dizziness when driving or operating machinery, so caution is advised. Finally, this medication contains lactose and should not be administered to patients with lactose intolerance or related genetic disorders.

Serious side effects

• Urticaria, angioedema including hypersensitivity reactions → severe allergic reactions
• Chest tightness, shortness of breath → respiratory issues
• Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS) → severe skin reactions
• Jaundice, hepatitis, increased transaminases, fatal and non-fatal liver failure → hepatic issues (jaundice)
• Severe headache, seizures, altered consciousness, visual disturbances, paralysis → severe

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• pruritus
• myalgia
• weakness
• diarrhea
• joint pain

This medication should be kept in a tightly closed container to prevent air or moisture from entering, and it is best stored at room temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the medication's effectiveness and safety.

Appearance

Pink, round film-coated tablets

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle