Rosutinem Tablet 5mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 milligrams once daily, and if more reduction in LDL cholesterol is required, the maintenance dose can be adjusted accordingly. The maintenance dose is usually 10 milligrams once daily, and most patients are adjusted at this dose. The maintenance dose should be appropriately adjusted at intervals of 4 weeks or more based on LDL cholesterol levels, treatment goals, and patient response, with a maximum of 20 milligrams per day.

This medication may not be suitable for certain patients. Firstly, those allergic to any components of this medication should not take it. Secondly, patients with severely impaired liver function or active liver disease should avoid this medication. Thirdly, patients with muscle diseases or issues related to muscles should also avoid this medication. Fourthly, patients taking the immunosuppressant cyclosporine should not use this medication. Fifthly, patients with significantly impaired kidney function are prohibited from taking this medication. Sixthly, women who are pregnant or breastfeeding should avoid this medication, and fertile women should use appropriate contraception. Seventhly, high-dose (40mg) administration is prohibited in patients at risk of myopathy. Eighthly, patients with lactose intolerance or genetic lactose metabolism disorders should not take this medication. Caution is advised when taking this medication. Individuals with poor liver function or those who consume alcohol heavily should undergo regular liver function tests both before and during treatment. If symptoms like muscle pain, muscle weakness, or cramps occur, patients should notify their doctor immediately, as muscle enzyme level tests may be required. The medication may need to be discontinued in cases of acute severe illness. Additionally, this medication can rarely cause severe muscle weakness or ocular muscle weakness, and if these symptoms occur, it should be discontinued immediately. This medication may interact with other drugs, thus it is mandatory to consult a doctor or pharmacist if you are taking other medications. Particularly, caution is needed when used with certain antiviral drugs, immunosuppressants, antifungals, antibiotics, and fibrate medications. If taken with oral contraceptives, it could affect contraceptive efficacy, so consultation with a physician is recommended. It is safest to avoid this medication during pregnancy or breastfeeding. Women who may become pregnant must use effective contraception while taking this medication. In case of overdose, since there is no specific antidote, immediate medical attention is necessary, as well as checks on liver function and muscle enzyme levels. Dizziness may occur while taking this medication, so caution is needed when driving or operating machinery. Lastly, this medication can rarely cause serious skin reactions; therefore, if symptoms like skin rash, itching, or swelling occur, use should be stopped immediately and medical attention sought.

Serious side effects

Hypersensitivity reactions including angioedema, hives, severe muscle weakness, rhabdomyolysis, severe skin adverse reactions (Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms), jaundice, hepatitis, acute renal failure, thrombocytopenia, severe swelling, dyspnea, cough, ocular muscle weakness, severe allergic reactions, severe liver damage and hyperbilirubinemia, hepatic failure, immune-mediated necrotizing myopathy, multifocal

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and hives
• muscle pain
• weakness
• thrombocytopenia

This medication should be stored in a tightly sealed container away from air and moisture, ideally at room temperature between 1°C and 30°C.

Appearance

Yellow round film-coated tablet

Package unit

100 tablets/box [(10 tablets/Alu-Alu) x 10], 30 tablets/bottle, 100 tablets/bottle