Qsymia Capsule 11.25mg/69mg

Adult dose

Take this medicine every morning, with or without food; avoid taking it in the evening because it may cause insomnia. 1) Take the initial dose of this medicine, 3.75mg/23mg, daily for 14 days. 2) After 14 days, take the recommended dose of 7.5mg/46mg for 12 weeks. 3) Assess weight loss. If taking 7.5mg/46mg does not result in a loss of at least 3% of body weight compared with the weight before the start of treatment, discontinue treatment or increase the dose. 4) If the dose is increased, take 11.25mg/69mg daily for 14 days. 5) After 14 days, take 15mg/92mg for 12 weeks. 6) Assess weight loss. If taking 15mg/92mg does not result in a loss of at least 5% of body weight compared with the weight before the start of treatment, discontinue treatment. *The 3.75mg/23mg and 11.25mg/69mg doses are for titration only. Discontinuation Because abrupt discontinuation may cause seizures, gradually discontinue the 15mg/92mg dose by taking it every other day for at least 1 week before completely stopping treatment. Patients with renal impairment Do not exceed 7.5mg/46mg once daily in patients with moderate (creatinine clearance [CrCl] of 30 or more and less than 50 mL/min) or severe (CrCl less than 30 mL/min) renal impairment. Renal impairment is determined by calculating CrCl using the Cockcroft-Gault equation with actual body weight. Patients with hepatic impairment Do not exceed 7.5mg/46mg once daily in patients with moderate hepatic impairment (Child-Pugh score 7-9).

This medication should not be used in combination with other appetite suppressants, as safety and efficacy have not been established for concurrent use. Taking this medication during pregnancy may harm the fetus, so if pregnancy occurs, it must be stopped immediately. Women of childbearing age should confirm pregnancy before starting treatment and undergo monthly pregnancy tests during treatment, using effective contraception. One of the ingredients in this medication, topiramate, can cause severe skin reactions, so if any abnormal skin symptoms occur, use should be discontinued immediately. Pregnant women, patients with glaucoma, hyperthyroidism, those on specific medications, patients with drug allergy history, children under 18 years of age, and those with cardiovascular diseases should not take this medication. Patients with impaired kidney or liver function, and those with a known allergy history to certain dyes in the medication should use it with caution. This medication may cause neurological symptoms, such as sensory disturbances, dizziness, taste abnormalities, insomnia, constipation, dry mouth, among others, and some patients may experience psychiatric symptoms, such as depression, anxiety, or cognitive impairment. Regular monitoring is necessary, as bicarbonate, potassium, and creatinine levels may change in blood tests. There is also a possibility of developing kidney stones, so if symptoms occur, consultation with a healthcare professional is needed. Additionally, this medication may increase heart rate, so patients with heart conditions or sensitivity to changes in heart rate should use caution. If any adverse reactions occur, medication should be discontinued or healthcare professionals should be consulted depending on the severity of the symptoms.

• Abnormal sensations
• dizziness
• altered taste
• insomnia
• constipation
• dry mouth
• headache
• sensory loss
• attention disorders
• depression

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is safe to store it at room temperature between 1 degrees and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness for a long time.

Appearance

Opaque yellow hard capsule containing white or almost white granules

Package unit

28 capsules/bottle