Rovast 10 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 mg once daily, and maintenance doses can be adjusted as needed for more LDL cholesterol reduction. The maintenance dose is typically 10 mg once daily, as most patients are adjusted at this dose. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, treatment goals, and patient response, typically at intervals of 4 weeks or more, with a maximum daily dose of 20 mg.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is between 5 mg and 20 mg once daily. The dosage should be adjusted according to the treatment goals for each individual patient.

This medicine should not be used in certain patients. For example, it should not be administered to patients who are allergic to this drug, have severe liver dysfunction, have muscle diseases, take specific immunosuppressants, have severe kidney dysfunction, are pregnant or breastfeeding, or have genetic issues such as lactose intolerance. Additionally, as this medicine can affect the liver or muscles, it should be used cautiously in patients who consume large amounts of alcohol or have a history of liver disease, those with hypothyroidism, those with renal impairment, and elderly patients; regular liver function tests and muscle-related tests should be performed before and during treatment. If symptoms such as muscle pain, weakness, fatigue, or warmth occur, medical personnel should be informed immediately, and if these symptoms are severe or if muscle damage levels increase significantly, discontinuation of the drug should be considered. This medicine can interact with other medications, so caution is needed when taken with certain antiviral drugs, immunosuppressants, antibiotics, and fibrate class drugs, as the risk of muscle damage may increase with concurrent use. Women who are pregnant or planning to become pregnant must consult with healthcare providers before taking this medicine and should use appropriate contraception. Breastfeeding should also be avoided, as use during pregnancy or nursing can pose risks to the fetus or infant. In case of overdose, there is no specific antidote, so treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored. Finally, this medicine is known not to significantly affect the ability to drive or operate machinery, but caution is advised due to possible side effects such as dizziness.

Serious side effects

Hives, hypersensitivity reactions including angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rashes with fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities associated with cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, and liver abnormalities.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• hematuria

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture. It should be kept in a location that avoids extreme heat or cold, preferably at a temperature between 1 and 30 degrees Celsius, which is room temperature.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle