Glida Tablet (Gliclazide)

Adult dose

Adjust individually for each patient. Swallow whole with more than 1/2 cup of water without chewing. Take orally once daily before breakfast or just before the first meal. The initial dose for monotherapy is 1 mg of gliclazide once daily, which can be increased by 1 mg every 1 to 2 weeks. Generally, additional benefits are rarely seen at doses greater than 4 mg, but up to 6-8 mg may be administered.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or those in a comatose state. Additionally, individuals who are allergic to this medication or its components, sulfonylureas, or sulfonamides should not take it. Patients with severely impaired liver or kidney function have not been experienced with this medication, so switching to insulin therapy is recommended in such cases. Women who are pregnant or may become pregnant, as well as nursing women, should not take this medication. Patients with severe infections, those undergoing surgery, or individuals with severe trauma should preferably receive insulin therapy. Caution is advised in cases of gastrointestinal disorders such as diarrhea or vomiting, as they may impair food absorption and increase the risk of hypoglycemia. This medication contains lactose, hence it should not be taken by patients with lactose intolerance or specific genetic problems. During the first week of taking this medication, there is a higher risk of hypoglycemia, so careful monitoring of blood sugar levels is essential. Particularly, elderly patients, those with poor nutritional status or who skip meals, those with imbalanced physical activity and carbohydrate intake, frequent alcohol consumers, and individuals with impaired kidney or liver function should exercise extra caution. Furthermore, the risk of hypoglycemia increases if this medication is overdosed, if there are endocrine disorders, or if other medications are being taken simultaneously. Symptoms of hypoglycemia can vary and may include headache, severe hunger, nausea, fatigue, anxiety, confusion, drowsiness, or decreased consciousness, so medical personnel should be notified immediately if these symptoms occur. This medication contains a dye called Yellow No. 5, so those allergic to this ingredient should be cautious. Hypoglycemia may occur with this medication, leading to various symptoms such as headaches, severe hunger, vomiting, fatigue, confusion, drowsiness, or decreased consciousness. Hypoglycemia is typically resolved quickly by consuming foods that contain sugar. Gastrointestinal symptoms such as blurred vision, nausea, abdominal pain, and diarrhea may also occur. Liver function abnormalities or blood-related problems may rarely occur, necessitating regular check-ups. Allergic reactions can present as itching, rash, or hives, and in severe cases may progress to breathing difficulties or shock, requiring immediate medical attention. Additionally, side effects such as hair loss and weight gain have been reported. It is important to take this medication regularly for blood sugar control, along with adhering to dietary and exercise regimens. In the event of hypoglycemic symptoms, immediate consumption of sugar is necessary, and carrying sugar at all times is advisable. During treatment, regular monitoring of blood sugar and urine tests is recommended to confirm drug efficacy, and dosage adjustments or changes in treatment methods may be needed as necessary. Caution is warranted when driving or operating machinery due to the risk of accidents from hypoglycemia. In situations of acute stress, blood sugar control may become more difficult, so treatment methods may need to change according to physician's instructions. This medication may interact with other drugs, so it's essential to inform healthcare providers of any other medications being taken. Particularly, caution is advised when taken alongside drugs that affect the enzymes that break down this drug in the liver. Additionally, using this medication with insulin, some anti-inflammatory drugs, antibiotics, or anticoagulants may affect blood sugar control. Some medications like beta-blockers may mask the symptoms of hypoglycemia, requiring additional caution. It is safer for pregnant or nursing women not to use this medication. This could harm the fetus, and during nursing, the medication can be passed to the baby. If necessary, switching to insulin therapy or discontinuing breastfeeding is recommended. For children under 18, the safety and efficacy of this medication have not been established, so it's advisable not to use it. Elderly patients may have reduced kidney function, requiring careful adjustment of this medication's dosage. Severe hypoglycemia can occur with overdose, so immediate contact with medical personnel is required for necessary emergency treatment. Following an overdose, measures such as inducing vomiting, blocking absorption of the drug, or gastric lavage may be necessary. If hypoglycemic coma is suspected, rapid injection of glucose should be administered, followed by close monitoring of blood glucose levels for 1 to 2 days.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, dyspnea, asthma attacks, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion of consciousness, visual disturbances, paralysis, significantly decreased urine output.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggressiveness
• decreased concentration
• reduced agility or initiative

This medication must be stored in a tightly sealed container to protect it from air and moisture. A storage temperature between 1°C and 30°C is advisable to safely maintain the drug's efficacy.

Appearance

Green rectangular tablet

Package unit

30 tablets/bottle, 300 tablets/bottle