Medication info
Alpieso 40mg (Esomeprazole Magnesium Hydrate)

Alpieso 40mg (Esomeprazole Magnesium Hydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Dihydrate›43.38mg / 1 tablet
Manufacturer / importer
(주)알피바이오
Appearance
Pink rectangular film-coated tablet
Packaging
28 tablets (14 tablets/Alu-Alu * 2)
Approval status
Active

MFDS item code 201903269 · Approved 2019.05.21 · Insurance code 661605050

Summary

Main use
Treatment of gastroesophageal reflux disease (erosive esophagitis, symptoms) and eradication of Helicobacter pylori (duodenal ulcer), treatment and prevention of gastric ulcers related to non-steroidal anti-inflammatory analgesics.
Who uses it
Adults · Children
Adult dosage
This medication must be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, another 4 weeks of treatment is necessary. - Maintenance therapy to prevent recurrence: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: once daily with 20 mg.
Children's dosage
Adolescents aged 12 and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, another 4 weeks of treatment is necessary. - Gastroesophageal reflux disease without esophagitis

Ingredients

Manufacturer
(주)알피바이오

Efficacy & effects

Treatment of gastroesophageal reflux disease (erosive esophagitis, symptoms) and eradication of Helicobacter pylori (duodenal ulcer), treatment and prevention of gastric ulcers related to non-steroidal anti-inflammatory analgesics.

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is used to treat various gastrointestinal disorders. It is effective for the treatment of gastroesophageal reflux disease (GERD) and erosive reflux esophagitis, as well as for long-term maintenance therapy to prevent recurrence. It is also used to treat and prevent recurrence in patients with duodenal ulcers and peptic ulcers caused by Helicobacter pylori infection. Additionally, it helps to relieve upper gastrointestinal symptoms related to the use of non-steroidal anti-inflammatory drugs (NSAIDs) and treats and prevents gastric ulcers and duodenal ulcers. It is also applied for the treatment of Zollinger-Ellison syndrome and maintenance therapy to prevent rebleeding of gastric or duodenal ulcers after intravenous administration. Thus, it is used to alleviate symptoms and prevent recurrence across various gastrointestinal disorders.

Dosage and Administration

Adult dosage

This medication must be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, another 4 weeks of treatment is necessary. - Maintenance therapy to prevent recurrence: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: once daily with 20 mg.

Children's dosage

Adolescents aged 12 and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. If not treated or symptoms persist, another 4 weeks of treatment is necessary. - Gastroesophageal reflux disease without esophagitis

Precautions

This medication should not be administered to patients who have hypersensitivity to its specific components or to benzimidazoles or who have experienced such reactions in the past. Also, when used in combination with amoxicillin or clarithromycin for the eradication of Helicobacter pylori, patients with hypersensitivity to these antibiotics should not use this medication. This medication cannot be used in combination with certain cardiovascular drugs or antivirals, and should be avoided by nursing women or patients with a history of myocardial infarction. While taking this medication, various side effects such as decreased blood cell counts, allergic reactions, nervous system symptoms, gastrointestinal issues, liver function abnormalities, skin rashes, etc., may occur, so consult with a healthcare professional immediately if any abnormal symptoms arise. Regular examinations are needed for prolonged use of this medication, particularly because magnesium levels may decrease, so periodic monitoring is recommended. Since this medication suppresses gastric acid secretion, it may increase bacterial growth in the gastrointestinal tract, so if diarrhea or infection symptoms persist, a hospital visit should be made immediately. Additionally, this medication has a high possibility of interacting with other drugs, so if other medications are being taken, it is essential to inform a doctor or pharmacist, particularly when taken with drugs affecting blood coagulation or antivirals. Data on the safety of this medication during pregnancy is limited, so it should be taken cautiously during pregnancy, and it is advisable not to use it while nursing. There is no specific antidote for overdose, so appropriate treatment according to symptoms must be obtained, and it should be stored in a safe place out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, anaphylactic reaction, shock, severe allergic reactions with high fever, severe rash, blisters, peeling skin, mucosal pain in the mouth/eyes, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), severe skin reactions, liver failure with or without jaundice

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disturbance, blurred vision, vertigo, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, gynecomastia, asthenia, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain, precordial pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature to preserve the medication's effectiveness for a long time.

Appearance and packaging

Appearance

Pink rectangular film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu * 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.