Acetal CR Tablets (Aceclofenac)

Adult dose

As aceclofenac, take 200 mg once a day. This medication should be taken whole without chewing or breaking. To minimize cardiovascular adverse reactions of this medication, it should be administered at the lowest effective dose for the shortest duration.

Patients who regularly consume more than three alcoholic beverages a day should consult with a doctor or pharmacist before taking this medication. Consuming this medication while heavily drinking may increase the risk of gastrointestinal bleeding. This medication may increase the risk to the cardiovascular and cerebrovascular system, thus those with risk factors such as heart disease, hypertension, diabetes, and smoking should use it with caution. It is advisable to use the lowest possible dose for the shortest duration, and symptoms and responses should be monitored periodically during treatment. Patients with a history of cerebral hemorrhage require special attention and medical supervision. This medication can increase the risk of serious gastrointestinal side effects including gastrointestinal bleeding, ulcers, and perforation, especially in the elderly. If symptoms of gastrointestinal bleeding occur during use, notify medical staff immediately, and patients at high risk should consider alternative treatments. Patients with active peptic ulcers or bleeding, those with a history of them, patients allergic to this medication or similar drugs, and patients with heart failure or severe renal and hepatic impairment should not take this medication. Pregnant women in late pregnancy and nursing mothers should also avoid this medication, and patients with inflammatory bowel disease or bleeding disorders need to be cautious. Patients with renal impairment, heart failure, hypertension, liver impairment, elderly individuals, and those with a history of asthma should use this medication with caution and consult medical staff if necessary. This medication may cause various side effects including dizziness, gastrointestinal disturbances, liver function abnormalities, and skin rashes, so any abnormal symptoms should be reported immediately. Severe skin reactions or serious allergic reactions such as anaphylaxis may occur, thus if initial symptoms are observed, the medication should be discontinued immediately. It is advisable to avoid dangerous tasks such as driving or operating machinery while taking this medication. Women planning to become pregnant are recommended to avoid using this medication, as temporary infertility may occur with prolonged use. There are many drug interactions; thus, it is essential to consult medical personnel regarding any other medications being taken. Overdose may lead to gastrointestinal irritation, hypotension, respiratory depression, and seizures, thus immediate medical attention is required. This medication should be kept out of the reach of children, and it should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), dyspnea, shock, anaphylactic reactions, gastrointestinal bleeding, gastrointestinal ulcers, perforation, digestive tract bleeding, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), bullous dermatitis, liver abnormalities (jaundice), serious liver-related adverse reactions (acute liver failure, liver necrosis, liver dysfunction), thromboembolic reactions in the cardiovascular system, myocardial infarction, stroke, acute coronary syndrome, myocardial infarction, heart failure.

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rashes
• skin reactions
• anemia
• leukopenia
• thrombocytopenia
• neutropenia
• hemolytic anemia

This medication must be stored in a tightly sealed container to prevent air and moisture infiltration. It is important to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

White rectangular controlled-release film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle