Medication info

Aliv Suspension

Prescription medicationSuspension경구Approval withdrawn
Ingredient · strength
L-Isoleucine›952mg / 1 packetL-Leucine›1904mg / 1 packetL-Valine›1144mg / 1 packet
Manufacturer / importer
알리코제약(주)
Appearance
A viscous suspension with a fruity flavor, white to yellowish, contained in aluminum foil pouches.
Packaging
20 pouches (20g/pouch x 20)
Approval status
Approval withdrawn

MFDS item code 201804900 · Notified 2018.12.04

This product's status changed to Approval withdrawn on 2025.03.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of hypoalbuminemia
Who takes it
Adults
Adult dose
Usually administered at a dose of 1 pouch orally three times a day after meals for adults.

Ingredients

Manufacturer
알리코제약(주)

Efficacy & effects

Improvement of hypoalbuminemia

  • Hypoalbuminemia
View approved original text

In patients with decompensated liver cirrhosis, this medication helps improve hypoalbuminemia even when dietary intake is sufficient. Hypoalbuminemia is a condition characterized by low serum albumin levels, which may reflect overall nutritional status and liver function deterioration. This medication supports liver function and raises serum albumin levels to improve the overall condition.

How to take

Adult dose

Usually administered at a dose of 1 pouch orally three times a day after meals for adults.

Precautions

This drug contains the artificial sweetener aspartame, which is broken down into phenylalanine in the body. Therefore, it should not be used by patients with phenylketonuria, a genetic disorder that requires restriction of phenylalanine intake. In addition, it should not be administered to patients with congenital maple syrup urine disease due to the risk of seizures or respiratory distress. When taking this medication, digestive symptoms such as constipation, diarrhea, abdominal distension, discomfort, and nausea may occur, and if these symptoms arise, the dosage should be reduced or temporarily discontinued. It may affect renal function, leading to an increase in BUN levels in blood tests, and there is also a risk of elevated serum ammonia levels due to metabolic disturbances, so dosage adjustments should be made if abnormal symptoms appear. Regarding liver function, AST, ALT, and bilirubin levels may rise, and side effects such as skin rash or itching, malaise, edema, and facial flushing have been reported. This medication is used in specific liver cirrhosis patients with low serum albumin levels and ascites or edema, where dietary guidance should be considered if adequate dietary intake is not possible. It should not be administered to patients with severe hepatic encephalopathy or markedly elevated total bilirubin levels where liver function is significantly impaired, as its effectiveness is not expected in such cases. As this drug contains only branched-chain amino acids, it cannot provide all essential amino acids, so patients should ensure sufficient protein and caloric intake from meals in accordance with their condition, and attention should be paid to potential nutritional deterioration with prolonged use. If serum BUN and ammonia levels rise, there is a risk of overdose, so caution is necessary, and if hypoalbuminemia does not improve after two months of use, alternative treatments should be considered. Elderly patients may be at greater risk of metabolic disturbances due to decreased physical function, thus caution is warranted during administration. Pregnant or breastfeeding women should only use this medication if the benefits of treatment outweigh the risks, as its safety has not been sufficiently established. Safety for children has not been proven, and experience with usage is limited, so caution is advised. This medication should be stored out of reach of children, and transferring it to another container is not advisable for quality maintenance and accident prevention. The aspartame content should be regulated to be below the WHO recommended levels, with a maximum daily dose of 2.4g for a 60kg adult.

Side effects and when to seek care immediately

Serious side effects

Edema (in the face, lower limbs, etc.) may correspond to severe swelling and should be monitored; however, there are no specific symptoms classified as definitively severe in the document.

Mild side effects

  • Constipation
  • diarrhea
  • abdominal bloating
  • abdominal discomfort
  • nausea
  • thirst
  • burping
  • abdominal pain
  • vomiting
  • loss of appetite
Show 11 more
  • epigastric pain
  • elevated serum ammonia levels
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • elevated bilirubin
  • rash
  • itching
  • malaise
  • edema (in the face, lower limbs, etc.)
  • flushing
  • facial reddening.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a light-resistant container. Additionally, it is important to store it at temperatures between 1 and 30 degrees Celsius to maintain the drug's effectiveness.

Appearance and packaging

Appearance

A viscous suspension with a fruity flavor, white to yellowish, contained in aluminum foil pouches.

Package unit

20 pouches (20g/pouch x 20)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.