Medication info
Ketovastatin 20 mg (Atorvastatin Calcium Trihydrate)

Ketovastatin 20 mg (Atorvastatin Calcium Trihydrate)

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Trihydrate›21.69mg / 1 tablet
Manufacturer / importer
한국코러스(주)
Appearance
White oval film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201800303 · Approved 2018.01.23 · Insurance code 647204950

Summary

Main use
Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia
Who uses it
Adults · Children
Adult dosage
For hyperlipidemia, the recommended initial dose is 10 mg of atorvastatin once daily. For patients requiring further reduction of LDL-cholesterol levels, treatment may begin with 20 mg or 40 mg once daily. The dose range is 10 to 80 mg once daily. Doses should be individualized based on treatment objectives and patient characteristics, and lipid levels should be analyzed 2 to 4 weeks after initiation or dose adjustment.
Children's dosage
The recommended initial dose for pediatric patients (10 to 17 years old) with heterozygous familial hypercholesterolemia is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. The administered dose should be adjusted based on the patient's treatment goals.

Ingredients

Manufacturer
한국코러스(주)

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia

  • Myocardial infarction
  • stroke
  • vascular procedures
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication is mainly used to reduce the risk of cardiovascular diseases. It particularly helps to lower the risks of myocardial infarction and stroke in adults at risk of coronary heart disease or patients with type 2 diabetes. It also reduces the likelihood of complications following vascular procedures and hospitalizations for stable angina and congestive heart failure. It is effective in treating hyperlipidemia and is used to improve cholesterol and triglyceride levels in patients with various types of dyslipidemia. It is beneficial for specific hypercholesterolemia patients who cannot control their condition through diet, especially in pediatric patients with family history or other cardiovascular disease risk factors. This medication is used to maintain cardiovascular health and reduce the risk of related diseases.

Dosage and Administration

Adult dosage

For hyperlipidemia, the recommended initial dose is 10 mg of atorvastatin once daily. For patients requiring further reduction of LDL-cholesterol levels, treatment may begin with 20 mg or 40 mg once daily. The dose range is 10 to 80 mg once daily. Doses should be individualized based on treatment objectives and patient characteristics, and lipid levels should be analyzed 2 to 4 weeks after initiation or dose adjustment.

Children's dosage

The recommended initial dose for pediatric patients (10 to 17 years old) with heterozygous familial hypercholesterolemia is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. The administered dose should be adjusted based on the patient's treatment goals.

Precautions

This medication carries a risk of muscle problems; therefore, if muscle pain or weakness worsens, or if creatine kinase levels increase significantly, use should be discontinued immediately. This medication should not be used in patients with certain diseases, in pregnant or nursing women, and in children under 10 years old. Patients with impaired liver or kidney function should use this medication with caution, and should consult a doctor immediately if symptoms of liver dysfunction or muscle pain appear. This medication can interact with various drugs, so patients taking other medications should inform their doctor or pharmacist. Particularly, patients with impaired liver function, heavy alcohol consumption, and the elderly need to be monitored carefully as they have a higher risk of muscle disorders or rhabdomyolysis. It is important to regularly check liver function and muscle status through blood tests while taking this medication. Women who are pregnant or may become pregnant should not take this medication and should use appropriate contraception while on it. Nursing mothers should also not take this medication and should discontinue breastfeeding while on it. There is no specific antidote for overdose, so treatment should be based on symptoms, and thorough liver function and muscle-related tests should be conducted. This medication should be stored out of reach of children and kept in its original container to prevent misuse or degradation of quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reaction, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, severe skin reaction, shortness of breath or difficulty breathing, asthma attacks, coughing accompanied by fever or respiratory difficulties, breathing problems, yellowing of the skin or eyes (jaundice), extreme lethargy, liver dysfunction (jaundice), sudden and

Mild side effects

  • Weakness
  • fatigue
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • rhinitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal bloating
  • indigestion
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • oropharyngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • dizziness
  • sensory disturbances
  • paresthesia
  • dysgeusia
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air exposure. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.