Medication info
Lyribea Capsule 300mg (Pregabalin)

Lyribea Capsule 300mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›300mg / 1 capsule
Manufacturer / importer
대웅바이오(주)
Appearance
Capsule with a reddish-brown upper part and a white lower part containing white or light yellow powder.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201706387 · Approved 2017.07.31 · Insurance code 694001440

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive treatment for partial seizures, relief of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication is to be taken orally, divided into two doses per day, regardless of food. 1. Neuropathic Pain - Peripheral neuropathic pain: The starting dose is 150 mg per day, which may be increased to 300 mg after 3-7 days, and if needed, it can be increased to a maximum of 600 mg at 7-day intervals. - Central neuropathic pain: The starting dose is 150 mg per day, which may be increased to 300 mg after one week.
Child dose
Administration is not recommended for children under 12 years of age and adolescents aged 12-17 due to insufficient safety and efficacy data.

Ingredients

Manufacturer
대웅바이오(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive treatment for partial seizures, relief of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia.
View approved original text

This medicine is used to treat peripheral and central neuropathic pain in adults. It is also effective as an adjunct in adults with epilepsy, especially those with partial seizures. Additionally, it helps alleviate symptoms of chronic pain conditions such as fibromyalgia. In summary, this drug is used for the treatment of nerve-related pain, certain seizures, and fibromyalgia.

How to take

Adult dose

This medication is to be taken orally, divided into two doses per day, regardless of food. 1. Neuropathic Pain - Peripheral neuropathic pain: The starting dose is 150 mg per day, which may be increased to 300 mg after 3-7 days, and if needed, it can be increased to a maximum of 600 mg at 7-day intervals. - Central neuropathic pain: The starting dose is 150 mg per day, which may be increased to 300 mg after one week.

Child dose

Administration is not recommended for children under 12 years of age and adolescents aged 12-17 due to insufficient safety and efficacy data.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors; therefore, patients should consult a doctor immediately if they experience depression or mood changes during treatment. Patients with hypersensitivity to this medication or lactose intolerance should not take it. Diabetic patients may need to adjust their blood glucose control medications due to potential weight gain. If allergic reactions such as angioedema occur, medication should be discontinued immediately. Elderly patients should be particularly cautious during the early stages of treatment due to the risk of careless accidents from dizziness or drowsiness. Blurred vision or changes in vision may occur, and patients should consult a doctor if symptoms arise. Discontinuation of this medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so it should be tapered off according to a doctor's instructions. There is a risk of drug abuse; therefore, patients with a history of substance abuse should be monitored closely. Patients with impaired kidney function may require dose adjustments. Patients with heart disease should be closely monitored while taking this drug. Caution is advised when used with opioid analgesics due to the enhanced central nervous system depressive effects, which may lead to respiratory depression. During early pregnancy, there is a risk of fetal deformities, so this medication should be avoided during pregnancy, and fertile women should use effective contraception. Breastfeeding women should either avoid this medication or discontinue breastfeeding, as it may be transmitted through breast milk and affect the baby. Caution is required when driving or operating dangerous machinery due to the risks of dizziness and drowsiness. In case of overdose, symptoms such as confusion, drowsiness, or seizures may occur, and immediate medical attention is necessary. Keep this medicine out of the reach of children and avoid transferring it to other containers. If severe rashes or swelling occur on the skin during the course of this medication, discontinue usage immediately and consult a doctor.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, edema, chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes, jaundice, extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion of consciousness, vision abnormalities, paralysis.

Mild side effects

  • Dizziness
  • drowsiness
  • dry mouth
  • increased appetite
  • decreased appetite
  • hypoglycemia
  • confusion
  • disorientation
  • irritability
  • depression
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  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
  • sexual hyperesthesia
  • restlessness
  • anxiety
  • mood swings
  • emotional lability
  • difficulty finding the right words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination issues
  • balance disorders
  • memory loss
  • attention disorders
  • loss of memory.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air and moisture. A cool place with a temperature between 15 and 30 degrees Celsius is suitable for storage.

Appearance and packaging

Appearance

Capsule with a reddish-brown upper part and a white lower part containing white or light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.