Hyaluronic Injection (Sodium Hyaluronate)

Adult dosage

Typically, for adults, one tube is administered once a week for 3 consecutive weeks into the knee joint or shoulder joint (intra-articular shoulder joint, subacromial bursa, or biceps tendon sheath). The number of administrations should be adjusted appropriately based on symptoms.

This medication should not be used in patients who have had an allergic reaction to its ingredients. It should also be used with caution in patients who have had allergic reactions to other drugs or have liver dysfunction or a history of liver disease. Since this drug is injected directly into the joint, care should be taken if there are skin disease or infections at the injection site. Severe allergic reactions or shock symptoms may occur during use, so if such symptoms appear, administration should be stopped immediately and appropriate treatment should be obtained. Moreover, swelling or rashes around the face or eyes, and itching may occur; if these symptoms appear, stop using the medication and consult a doctor. Transient pain, swelling, redness, or warmth at the injection site may occur, and symptoms like nausea, vomiting, and fever may also develop. In the case of severe arthritis, it is advisable to use this drug after inflammation has subsided, and stabilizing the injection site afterward is helpful. If the medication leaks outside the joint, it may cause pain, so it must be injected accurately into the joint cavity. Maintain sterility during the injection, and if symptoms do not improve, it should only be administered up to 3 times at most. If there is fluid accumulation in the joint, it may be necessary to drain it prior to injection. This medication is not for use intra-vascularly or in the eyes, and a needle gauge of 22-23 is most appropriate. Caution should also be taken as the drug may precipitate when used with certain disinfectants. Use during pregnancy or in women who may become pregnant should be decided with caution, and since this drug can be transmitted through breast milk, breastfeeding should be avoided during administration. Safety in children has not been established, and it should only be used cautiously when absolutely necessary. Elderly patients may have reduced bodily functions, so extra caution is required.

Serious side effects

Shock symptoms.

Mild side effects

Swelling (facial, eyelid, etc.), facial flushing, rash, itching, pain (mainly transient pain after administration), enlargement, edema, redness, warmth, localized severe pressure sensation, nausea, vomiting, fever, exacerbation of local inflammation symptoms.

This medication should be stored in a sealed container to prevent exposure to air and light. It is best stored in a dark place away from direct sunlight. The temperature should be maintained between 1 degree to 30 degrees Celsius for safe use.

Appearance

A colorless, transparent, viscous liquid contained in a glass or plastic tube sealed at both ends with rubber stoppers (part of a pre-filled syringe system).

Package unit

(2.0mL/tube)×3