Exrofine Tablet 10/160 mg

Adult dose

The recommended dose for this medication is 1 tablet once daily, taken with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients with mild to moderate renal impairment, dosage adjustment is not necessary, but patients with severe renal impairment and those on dialysis should not be administered this medication. In patients with mild to moderate hepatic impairment, the daily dose of valsartan should not exceed 80 mg; severe hepatic impairment patients should not be treated with this drug.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established; therefore, administration is not recommended.

This drug can cause severe harm to the fetus if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients who have allergies to this drug's components or similar medications, pregnant or breastfeeding women, patients with severe renal or liver dysfunction, and patients with certain heart diseases should not take this medication. Patients with low sodium or fluid levels in the body should improve their condition before taking this medication, and if symptoms of hypotension appear during use, they should lie down immediately and seek medical treatment if necessary. Patients with high potassium levels or those taking medications that may increase potassium levels should have their potassium levels checked frequently. Patients with problems in renal blood vessels or those who have recently undergone kidney transplants should exercise caution as this medication may affect kidney function. This medication can cause angioedema, which involves symptoms such as swelling of the face, lips, or tongue; if these symptoms occur, the medication should be discontinued immediately. Patients with heart failure or post-myocardial infarction should closely monitor changes in kidney function while taking this medication, and acute myocardial infarction patients should be cautious as this medication may exacerbate angina or myocardial infarction. Co-administration with other RAAS acting drugs during hypertension treatment may increase the risk of hypotension, worsening renal function, and hyperkalemia, so co-administration should be avoided, and if unavoidable, blood pressure and renal function should be tested frequently. Caution should be exercised as dizziness or fatigue may occur during driving or operating machinery. In patients with compromised liver function, the dosage should be limited, and in cases of overdose, hypotension, increased heart rate, and in severe cases, shock may occur, requiring immediate medical treatment. Additionally, this drug is not recommended for children under 18 years of age as safety and efficacy have not been adequately established.

Serious side effects

Urticaria, severe swelling (angioedema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress associated with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver dysfunction (jaundice), sudden and

Mild side effects

• Headache
• dizziness
• drowsiness
• paresthesia
• vertigo
• tinnitus
• tachycardia
• palpitations
• syncope
• orthostatic hypotension

This medication must be stored in a tightly sealed container to protect it from exposure to air or moisture. It is important to maintain storage temperature at room temperature between 1°C and 30°C. This will help preserve the effectiveness and safety of the medication for a longer period.

Appearance

Bright yellow oval film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2)