Medication info
Nutra Tablets

Nutra Tablets

Prescription medicationTablet경구
Ingredient · strength
Acetaminophen›325mg / 1 tabletTramadol Hydrochloride›37.5mg / 1 tablet
Manufacturer / importer
안국뉴팜(주)
Appearance
Pale yellow oblong film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201603986 · Approved 2016.06.27 · Insurance code 053600230

Summary

Main use
Relief of moderate to severe acute and chronic pain
Who takes it
Adults
Adult dose
In children over 12 years of age and adults: The dosage should be adjusted according to the patient's pain level and treatment response. It is recommended to administer an initial dose of 2 tablets, with subsequent doses spaced at least 6 hours apart, not exceeding 8 tablets per day. Administer the effective lowest dosage for the shortest period possible. Avoid excessive long-term use of this medication, and if long-term administration is necessary due to disease characteristics and severity, regular monitoring should be conducted to assess the necessity of continued use. Elderly: Administer the usual adult dose, but for individuals over 75 years, the half-life of tramadol may increase by 17% when administered orally, so it should be dosed at intervals of at least 6 hours. Patients with renal impairment: For moderate renal impairment (creatinine clearance of 10-30 ml/min), the dosing interval should be extended to 12 hours. For severe renal impairment (creatinine clearance less than 10 ml/min), this medication is not recommended. Tramadol is very slowly eliminated during blood dialysis, so it is not typically necessary to re-administer this medication post-dialysis to maintain analgesic effect. Patients with liver impairment: Care should be taken to extend the dosing interval for patients with moderate liver impairment. This medication should not be administered to patients with severe liver impairment.

Ingredients

Manufacturer
안국뉴팜(주)

Efficacy & effects

Relief of moderate to severe acute and chronic pain

  • Acute pain
  • chronic pain
View approved original text

This medication is used to relieve acute or chronic pain ranging from moderate to severe.

How to take

Adult dose

In children over 12 years of age and adults: The dosage should be adjusted according to the patient's pain level and treatment response. It is recommended to administer an initial dose of 2 tablets, with subsequent doses spaced at least 6 hours apart, not exceeding 8 tablets per day. Administer the effective lowest dosage for the shortest period possible. Avoid excessive long-term use of this medication, and if long-term administration is necessary due to disease characteristics and severity, regular monitoring should be conducted to assess the necessity of continued use. Elderly: Administer the usual adult dose, but for individuals over 75 years, the half-life of tramadol may increase by 17% when administered orally, so it should be dosed at intervals of at least 6 hours. Patients with renal impairment: For moderate renal impairment (creatinine clearance of 10-30 ml/min), the dosing interval should be extended to 12 hours. For severe renal impairment (creatinine clearance less than 10 ml/min), this medication is not recommended. Tramadol is very slowly eliminated during blood dialysis, so it is not typically necessary to re-administer this medication post-dialysis to maintain analgesic effect. Patients with liver impairment: Care should be taken to extend the dosing interval for patients with moderate liver impairment. This medication should not be administered to patients with severe liver impairment.

Precautions

This medication may cause liver damage if taken by individuals who regularly consume more than three alcoholic beverages daily; it is essential to consult a physician or pharmacist. If a rash or hypersensitivity reaction occurs while taking this medication, it should be discontinued immediately, and a physician should be consulted. Tramadol, one of the active ingredients in this medication, may increase the risk of seizures if taken above the recommended dose, and this risk is higher when used with certain antidepressants or narcotics. Patients with acute or severe bronchial asthma may be at high risk for respiratory depression when taking this medication, so it should only be administered in a medically equipped facility. Concurrent use of this medication with alcohol or central nervous system depressants can lead to severe sedation, respiratory depression, and even death; therefore, such combinations should be avoided. Patients with elevated intracranial pressure or head injuries should be cautious as respiratory depression from this medication may worsen their symptoms. This medication can lead to physical and psychological dependence, so careful monitoring is required when used for long periods. Patients with impaired liver function should consult a physician before use, as the components of this medication may severely impact liver health. Patients with certain genetic metabolic traits may experience increased levels of active metabolites, leading to a higher risk of respiratory depression and should be cautious. This medication should not be given to children under 12 years of age or adolescents under 18 years of age who have undergone tonsillectomy or adenoidectomy; adolescents aged 12 to under 18 should also avoid it if they have specific risk factors. This medication may induce sleep apnea or hypoxia, requiring ongoing evaluation of symptoms and possible dosage adjustments or discontinuation. During treatment, there is a risk of hyponatremia, so elderly patients or those with risk factors should have their serum sodium levels checked periodically. This medication interacts with several other drugs, which may increase the risk of seizures, serotonin syndrome, or respiratory depression; it is necessary to inform healthcare providers of all medications being taken. Pregnant or breastfeeding women should consult a physician before taking this medication, as it may pose risks to the fetus or newborn; it is advisable to avoid its use during breastfeeding. Caution is advised due to potential drowsiness or dizziness while driving or operating machinery after taking this medication. Overdosing on this medication can result in severe respiratory depression, seizures, liver damage, and even fatal side effects; therefore, prescribed dosages should always be adhered to, and emergency care should be sought immediately in case of overdose. Store this medication out of reach of children to prevent accidental ingestion.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory abnormalities, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, disorientation, visual disturbances, paralysis, urinary retention

Mild side effects

  • Decreased appetite
  • insomnia
  • depression
  • dizziness
  • headache
  • drowsiness
  • nausea
  • vomiting
  • constipation
  • dry mouth
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  • diarrhea
  • indigestion
  • abdominal pain
  • abdominal discomfort
  • flatulence
  • pruritus
  • sweating
  • rash
  • fatigue
  • flushing
  • hypoglycemia
  • anxiety
  • nervousness
  • emotional instability
  • euphoria
  • decreased libido
  • sleep disturbances
  • confusion
  • disorientation
  • excitement
  • abnormal dreams
  • drug abuse
  • hallucinations
  • withdrawal syndrome
  • migraine
  • somnolence
  • sensory loss
  • tremors
  • paresthesia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent airflow and ideally kept at a temperature between 1 degree and 30 degrees Celsius. Storing it this way may help maintain its effectiveness for a longer period.

Appearance and packaging

Appearance

Pale yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.