Amadol ER Extended-release Tablet

Adult dose

The dosage is adjusted according to the patient's level of pain and therapeutic response. An initial dose of 1 tablet is administered, and the interval between doses should be at least 12 hours. Do not exceed 4 tablets in one day. In cases where prolonged treatment is necessary, regular monitoring should be conducted. Elderly patients should be administered the usual adult dosage, but those aged 75 and older should take it at intervals of at least 12 hours.

This medication can put a strain on the liver, so individuals who regularly consume more than three alcoholic drinks a day should consult their doctor or pharmacist before taking it. This medication can rarely cause serious allergic skin reactions; thus, if any rash or other hypersensitivity reactions occur, the use of this medication should be immediately discontinued, and a specialist should be consulted. There is a risk of seizures associated with this medication; therefore, special precautions should be taken for patients with a history of seizures or those taking drugs that can induce seizures. In cases of severe respiratory diseases, there is a risk of respiratory suppression when using this medication; thus, it should be administered under strict supervision by medical staff. Combining this medication with alcohol or central nervous system depressants can cause severe drowsiness, respiratory suppression, and coma; hence co-administration should be avoided or used with caution. Patients with increased intracranial pressure or head injuries may find their symptoms worsening due to the respiratory depression effect of this medication. This medication can cause psychological and physical dependence, so careful monitoring for dependence is necessary with prolonged use. Patients with impaired liver function may experience liver damage due to the ingredients in this medication; hence they should consult with a doctor before use. This medication should not be given to children, especially those under 12 years of age, or to adolescents under 18 who have had tonsillectomy or adenoidectomy. Additionally, adolescents aged between 12 and 18 should avoid use if any special risk factors are present. Electrolyte imbalances such as hyponatremia may occur during the use of this medication; therefore, elderly patients or those with risk factors should be closely monitored for symptoms. Patients should confirm whether they have any allergies to its ingredients before taking this medication, and it should not be administered to those in specific conditions such as certain drug intoxications, severe respiratory depression, or brain damage. Drowsiness or dizziness may occur during the intake; thus, it is safest to avoid driving or handling hazardous machinery. In case of overdose, serious side effects such as respiratory suppression, coma, and liver damage may occur, so immediate emergency measures should be undertaken, and treatment should be received at a specialized medical facility. This medication can interact with several other drugs; therefore, if you are taking other medications, you must inform your healthcare provider, especially when used in conjunction with antidepressants, antibiotics, or central nervous system depressants. Pregnant or breastfeeding women should carefully consider the risks and benefits of using this medication, and during breastfeeding, because this medication can be passed into breast milk and affect the baby, it is preferable to avoid use.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, difficulty breathing or wheezing, asthma attack, cough with fever and respiratory abnormalities, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Weakness
• fatigue
• flushing
• rigidity
• fainting
• withdrawal symptoms
• hypertension
• worsening hypertension
• hypotension
• arrhythmia

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is safe to store it at room temperature between 1 to 30 degrees Celsius.

Appearance

Light yellow, rectangular extended-release film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle