Mupain Semi Sustained-Release Tablet

Adult dose

Adjust the dosage based on the degree of the patient's pain and treatment response. Administer an initial dose of 2 tablets, and thereafter, maintain a minimum interval of at least 12 hours between doses. Do not exceed 8 tablets per day. Avoid prolonged use beyond what is necessary, and in cases requiring long-term treatment, regular monitoring is necessary. Side effects such as nausea, vomiting, itching, constipation, dizziness, drowsiness may occur; hence, monitor patient response closely.

This medication may cause liver damage if taken by individuals who regularly consume more than three alcoholic drinks daily, so consultation with a doctor or pharmacist is essential. This medication can rarely cause serious skin reactions; if a skin rash or allergy symptoms occur, discontinue use immediately and consult a healthcare professional. Due to the presence of tramadol, exceeding the recommended dose may increase the risk of seizures, and the risk of seizures is also heightened when taken with certain antidepressants or other central nervous system medications. In patients with severe respiratory diseases, this medication may inhibit respiration; therefore, it should only be administered in an environment where medical equipment is prepared. Taking this medication with alcohol or benzodiazepines may result in severe sedation, respiratory suppression, or coma, requiring caution. Patients with elevated intracranial pressure or head injuries should use this medication cautiously as it may worsen brain pressure through respiratory suppression. As tramadol is an opioid medication, it may induce physical and psychological dependence, making careful monitoring necessary for long-term use. Patients with impaired liver function may experience liver damage due to the acetaminophen contained in this medication, so it must only be taken after consulting a physician. Particularly, patients who are ultra-rapid metabolizers for CYP2D6 should be monitored for dosage adjustments due to increased risk of respiratory suppression resulting from rapid drug metabolism. This medication should not be administered to children under the age of 12 or to individuals under 18 years who have undergone tonsillectomy or adenoidectomy; adolescents aged 12 to 18 should also avoid use if they have risk factors. Elderly patients or those at risk for hyponatremia should regularly check their blood sodium levels due to the possibility of developing hyponatremia. Patients with hypersensitivity to any components of this medication, central nervous system drug intoxication, severe respiratory depression, head injuries, etc., should not be administered this medication. Pregnant and breastfeeding individuals must consult a doctor before using this medication, as it may affect the fetus or newborn; especially during breastfeeding, the medication can be transmitted through breast milk, posing risks to the baby. Caution is needed when driving or operating machinery, as dizziness or drowsiness may occur due to this medication. In the case of overdose, severe respiratory depression, liver damage, etc., may occur, requiring immediate medical attention; treatment may involve respiratory support and antidotes. During treatment with this medication, avoid taking other tramadol or acetaminophen products concurrently. This medication is an opioid drug, which has the potential for dependence or abuse, and withdrawal symptoms may occur, so abrupt discontinuation should be avoided. When used in conjunction with other central nervous system depressants, reduce the dosage and closely monitor the patient's condition. Patients with impaired liver, kidney, or heart function and elderly patients need to exercise increased caution when taking this medication.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough + fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination difficulties

Mild side effects

• Weakness
• fatigue
• flushing
• rigidity
• fainting
• withdrawal symptoms
• hypertension
• worsening hypertension
• hypotension
• arrhythmia

This medication should be stored in a sealed container, protected from air and moisture. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius, avoiding extremely hot or cold places.

Appearance

Pale yellow, round, sustained-release film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle