Secoxib Capsule 200mg (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted according to the patient and may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, a dose of up to 400 mg per day may be administered. If no effect is observed after 6 weeks of administration at 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg administered on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug carries a risk of gastrointestinal bleeding for individuals who regularly consume more than three standard drinks per day, so consultation with a doctor or pharmacist is necessary. This drug may increase the risk of serious cardiovascular side effects such as thrombotic reactions, myocardial infarction, and stroke; therefore, it should be used for the shortest duration and at the lowest effective dose possible. If cardiovascular symptoms such as chest pain, shortness of breath, weakness, or speech impairment occur during use, notify healthcare professionals immediately. This drug can cause serious gastrointestinal adverse reactions such as gastrointestinal perforation, ulcer, or bleeding, particularly in elderly patients or those with a history of gastrointestinal disorders, who should exercise extra caution. If symptoms of gastrointestinal bleeding such as epigastric pain, dyspepsia, melena, or hematemesis occur, immediate evaluation and treatment are required. This drug should not be given to patients with a history of specific allergies, significant liver or kidney disease, active peptic ulcer disease, heart failure, or to pregnant or breastfeeding women. Patients with impaired liver or kidney function, asthma, hypertension, or a history of cardiovascular diseases should use this drug cautiously and require regular monitoring and testing. This drug may interact with various medications, so inform healthcare professionals of any other medications you are taking. Pregnant women or those who might become pregnant should avoid taking this drug, and if pregnancy occurs while taking it, the drug should be discontinued immediately. It is also recommended not to administer this drug to breastfeeding women, and consider stopping either breastfeeding or the medication. Elderly patients may have decreased kidney, liver, or heart function, requiring special caution and possible dose adjustments. Dizziness or drowsiness may occur while taking this drug, so it is advisable to avoid driving or operating machinery. Long-term use may necessitate regular blood tests and checks on liver and kidney function to monitor for any abnormalities. If hypersensitivity reactions such as skin rash, fever, or itching occur after taking this medication, discontinue use immediately and consult healthcare professionals.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tone increase, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, sensory anomaly, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, vasculitis, thrombophlebitis, deep vein thrombosis, cerebral hemorrhage, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, increased ALT, increased AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursal sac, arthralgia, arthritis, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fracture, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, pleuritis, contact dermatitis, injection site reaction, cutaneous nodules, ageusia, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, chest pain, anaphylaxis reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, pulmonary embolism, interstitial pneumonia, hepatitis, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, female infertility

This medication should be stored in a tightly sealed container to prevent air ingress, ideally at room temperature between 15 to 30 degrees Celsius. This helps maintain the drug's effectiveness and prevent degradation.

Appearance

A white capsule filled with a white to yellowish powder with yellow bands on the top and bottom

Package unit

30 capsules/bottle, 100 capsules/bottle