Huresto 5 mg (Rosuvastatin Calcium)

Adult dose

This medication can be administered at any time of the day, regardless of meals. The initial dose is 5 mg once daily, and if a greater reduction in LDL cholesterol levels is needed, the maintenance dose can be adjusted. The maintenance dose is typically 10 mg once daily for most patients who are adjusted to this dosage. Adjustments should be made at intervals of 4 weeks or longer based on LDL cholesterol levels, therapeutic goals, and patient response. The maximum daily dose is 20 mg.

Child dose

The usual dose range is 5 mg to 20 mg once a day. The dosing should be adjusted based on the therapeutic goals for each individual patient, and dose adjustment should be made at intervals of 4 weeks or more. For children under 10 years old, safety and efficacy have not been established.

This drug should not be used in certain patients. For example, it should not be administered to patients with allergies to its components, severely impaired liver function, muscle diseases, those taking specific immunosuppressants, those with severely reduced kidney function, pregnant or nursing women, and those at risk for muscle disease. Caution should be exercised when administering this drug to patients with compromised liver function or those who consume large amounts of alcohol, and it is advisable to perform repeat liver function tests before and during treatment. Additionally, if symptoms of muscle pain or weakness occur, medical personnel should be notified immediately and an examination should be conducted. Patients at high risk of muscle damage, such as those with kidney disorders, hypothyroidism, a family history or past incidents of muscle toxic reactions, the elderly, and those with alcohol abuse, should use this drug with increased caution and regular muscle-related examinations are necessary. This drug contains lactose and should not be administered to patients with lactose intolerance. While taking this drug, rare side effects such as headache, dizziness, indigestion, skin rash, and muscle pain may occur, and in severe cases, serious muscle damage such as myositis or rhabdomyolysis may develop. Pregnant or nursing women should not take this medication, and women who might become pregnant should use appropriate contraception. This drug may interact with other medications, so caution is required, especially when taken with specific antiviral drugs, immunosuppressants, antibiotics, and fibrate medications. When taken with certain drugs, the blood concentration of this medication may increase, raising the risk of muscle damage. In case of overdose, there is no specific antidote, and symptom-based treatment and liver function and muscle enzyme examinations are necessary. Caution should be exercised as dizziness may occur during driving or operating machinery. If severe skin reactions, liver function abnormalities, severe muscle pain, or other abnormal symptoms occur while taking this drug, consumption should be stopped immediately, and medical personnel should be consulted.

Serious side effects

• Allergic reactions including hives, angioedema
• Severe swelling (edema)
• Chest tightness
• Difficulty breathing, dyspnea, cough
• Severe rash, blisters, skin peeling, mucous membrane pain in mouth/eyes accompanied by high fever
• Stevens-Johnson syndrome
• Drug reaction with eosinophilia and systemic symptoms (DRESS)
• Severe skin abnormal reactions on the skin
• Yellowing of the skin or eyes (jaundice)
• Hepatitis, both fatal and non-fatal liver failure

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• hematuria

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is best to store it at normal room temperature between 1°C and 30°C, avoiding excessively hot or cold environments.

Appearance

Yellow round film-coated tablet

Package unit

PTP - 30 tablets/PTP [(15 tablets/PTP x 2)]