Dongkwang Clarithromycin Tablet

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, reduce the dose by half, i.e., administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this drug to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this drug per dose, twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: For 14 days, administer 500mg (potency) of this drug 3 times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults. Children under 12 years: Use clarithromycin dry syrup.

This medication should not be used by patients who are allergic to specific components. Patients who have had allergic reactions to similar classes of antibiotics should also not receive it. It may be hazardous to take with certain medications that can affect heart rhythms, so co-administration should be avoided. It is also recommended that patients with severe cardiac diseases or significant liver or kidney impairment do not use this medication. Pregnant or breastfeeding women are advised not to take this medication. It is not administered to patients with central nervous system infections. This medication should not be given to patients with genetic metabolic disorders due to the lactose content. Patients with impaired liver or kidney function should use this medication cautiously, and dose adjustments may be necessary. Elderly patients should also be careful when using this medication. When taken with other antibiotics or specific medications, there is a risk of drug interactions; therefore, consultation with a specialist is advised. This medication can result in rare but severe allergic reactions or skin rash, liver dysfunction, kidney problems, or central nervous system symptoms, so if any unusual symptoms occur, notify healthcare professionals immediately. Long-term or high-dose use may lead to hearing impairment or tinnitus, so caution is necessary. If symptoms such as diarrhea, abdominal pain, or fever appear during treatment, there may be a risk of gastrointestinal infections or inflammation, and usage should be stopped immediately with consultation from a physician. Care should also be taken during driving or operating machinery as dizziness or confusion may occur. Overdosage can cause gastrointestinal disturbances or neurological symptoms, so prescribed dosages must be strictly adhered to. This medication is usually stored at room temperature away from air and moisture, and refrigeration is not required.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disturbance, loss of appetite, constipation, discoloration of stools, membrane colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste perversion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated serum creatinine, elevated blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, thoracic pain, chills, fatigue, abnormal albumin globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine discoloration, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, rash, sweating, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, it should be kept away from direct sunlight and in a dry place, maintaining a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle