Gloem Tablet

Adult dose

This medication is administered 1 to 2 times a day before or with meals. Typically, treatment is initiated with a lower dose, adjusting based on the patient’s currently prescribed medications and blood sugar levels. In clinical trials, the initial daily dose was 2mg of Glimperide/Metformin Hydrochloride 500mg, and based on blood monitoring results, it may be gradually increased up to 8mg of Glimperide/Metformin Hydrochloride 2000mg.

This medication can cause severe lactic acidosis or hypoglycemia, especially in cases where renal function has dramatically declined, which may increase the risk of lactic acidosis due to the accumulation of Metformin. It is important to temporarily discontinue this medication and consult a physician if dehydration symptoms occur. Moreover, patients with impaired renal function or those taking certain medications should be particularly cautious when using this medication. This medication should not be administered to patients with insulin-dependent diabetes or those with acute metabolic acidosis, severe liver or kidney dysfunction. It is also safest not to use this medication in pregnant or breastfeeding women. Patients at high risk of hypoglycemia, such as the elderly or those with irregular meal intake, require especially careful monitoring. Various side effects may occur during the use of this medication, such as gastrointestinal disturbances, skin allergies, and blood abnormalities, so patients should consult a physician immediately if symptoms arise. Blood sugar control should be regularly monitored, and renal function tests should be routinely performed. This medication may interact with other drugs, so it’s necessary to consult healthcare professionals when used in combination. In cases of overdose, hypoglycemia or lactic acidosis may occur, requiring immediate medical attention. Caution should be exercised when driving or operating machinery, as hypoglycemia or agility disorders may occur. Particular care is needed when administering this medication to children and the elderly, especially since elderly patients may require dosage adjustments due to reduced renal function. Store this medication in a tightly sealed container to prevent exposure to air and moisture. It is best to maintain storage temperatures between 1 degree and 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reaction, high fever accompanied by severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe skin atypical reactions, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, seizures, loss of consciousness

Mild side effects

Nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain, visual impairment due to changes in blood sugar levels, metallic taste, erythema, itching, rash, nausea, diarrhea, indigestion, palpitations, dizziness, hair loss, weight gain, thrombocytopenia, leukopenia, hemolytic anemia, erythropenia, agranulocytosis, pancytopenia, increased liver enzymes, liver function impairment, hepatitis, allergic vasculitis, photosensitivity

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. Storage temperatures should be maintained at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help the medication retain its effectiveness for a longer period.

Appearance

White rectangular film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle