Silica Capsule 75mg (Pregabalin)

Adult dose

This medication is administered orally, divided into two doses per day, without regard to food. Peripheral neuropathic pain: Starting dose of 150 mg per day, which can be increased to 300 mg per day after 3-7 days if needed, up to a maximum of 600 mg per day at intervals of 7 days. Central neuropathic pain: Starting dose of 150 mg per day, increased to 300 mg per day after 1 week, and then subsequent increase to 600 mg per day.

Child dose

Safety and efficacy data for children under 12 years and adolescents aged 12-17 are insufficient, so administration is not recommended.

This medication may increase the risk of suicidal thoughts or behavior, as well as mental health issues such as depression. Patients and caregivers should inform healthcare providers immediately if such symptoms occur. This medication should not be administered to patients with allergies to its components or certain genetic diseases. Diabetic patients may experience weight gain that could affect blood sugar control, which may require adjustments to the dosage of blood sugar medications. If signs of allergic reactions such as angioedema occur, discontinue the medication immediately, paying attention to symptoms of swelling around the face or mouth. Elderly patients should be cautious with the use of this medication due to a higher risk of dizziness and drowsiness, which may increase the risk of falls, especially during the initial days of therapy until they get accustomed to the symptoms. Transient blurred vision or changes in vision may occur, and if such symptoms arise, the patient should consult with a healthcare provider. Abrupt discontinuation of this medication can lead to withdrawal symptoms such as insomnia, headaches, and anxiety; therefore, the dose should be reduced gradually according to a physician's instructions. Patients with a history of substance misuse should be monitored closely for signs of misuse while on this medication. Patients with impaired kidney function may require dose adjustments for this medication. Patients with heart disease should use this medication with caution as it may worsen symptoms of congestive heart failure. Taking this medication with opioid analgesics can significantly increase the risk of central nervous system depression, leading to serious side effects such as respiratory difficulties, and vigilance is necessary. During early pregnancy, this medication may pose a risk of congenital malformations to the fetus, and pregnant women are advised against using it. Women of childbearing age should employ effective contraceptive methods. Lactating women should consult a healthcare provider regarding the potential transfer of this medication into breast milk, which could affect the baby; therefore, nursing should be avoided during treatment or discussed with a professional. This medication may cause dizziness and drowsiness, so caution should be exercised when driving or operating dangerous machinery until symptoms have been confirmed. In case of overdose, symptoms may include confusion, drowsiness, depression, seizures, and treatment such as hemodialysis may be required. Keep this medication out of reach of children, and do not transfer it to another container. If the patient experiences severe rashes, red spots, blisters on the skin while taking this medication, they should stop taking it immediately and consult a healthcare provider.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, difficulty breathing or tightness in the chest, asthma attack, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, changes in urine output.

Mild side effects

• Dizziness
• drowsiness
• confusion
• disorientation
• irritability
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, avoid storing it in excessively hot or cold conditions, and it is best kept at room temperature, between 15 to 30 degrees Celsius.

Appearance

A hard capsule with a reddish-brown upper part and a white lower part containing white powder.

Package unit

30 capsules/bottle, 100 capsules/bottle, 300 capsules/bottle