Medication info
Vytorin 10/10

Vytorin 10/10

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletSimvastatin›10mg / 1 tablet
Manufacturer / importer
(주)바이넥스
Appearance
White to pale yellow, biconvex, rectangular tablets
Packaging
30 tablets (10 tablets/PTP x 3)
Approval status
Active

MFDS item code 201007276 · Notified 2010.11.30 · Insurance code 643103210

Summary

Main use
Improvement of cholesterol and lipids in hypercholesterolemia (primary, homozygous familial) and mixed dyslipidemia
Who takes it
Adults
Adult dose
This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with the generally recommended starting dose being 10/20 mg daily. For patients who require less reduction in LDL cholesterol, one may start at 10/10 mg daily. For patients with homozygous familial hypercholesterolemia, the recommended dose is 10/40 mg daily administered in the evening.

Ingredients

Manufacturer
(주)바이넥스

Efficacy & effects

Improvement of cholesterol and lipids in hypercholesterolemia (primary, homozygous familial) and mixed dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • atherosclerotic vascular disease due to hypercholesterolemia
  • dyslipidemia
View approved original text

This medication helps lower elevated total cholesterol and LDL cholesterol levels in patients with primary hypercholesterolemia, particularly heterozygous familial and non-familial hypercholesterolemia, reduce ApoB protein and triglycerides, and increase HDL cholesterol, which is considered 'good' cholesterol. It can also be used alone or in conjunction with other treatments for patients with homozygous familial hypercholesterolemia. This drug is used alongside non-drug measures such as dietary therapy, and appropriate treatment should be pursued after checking for other secondary causes. Patients with acute coronary events should have their cholesterol levels checked upon hospitalization, and treatment started if necessary. Overall, this medication plays a vital role in reducing risk factors associated with hypercholesterolemia and preventing cardiovascular diseases, thus being effectively used in the treatment of hypercholesterolemia.

How to take

Adult dose

This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with the generally recommended starting dose being 10/20 mg daily. For patients who require less reduction in LDL cholesterol, one may start at 10/10 mg daily. For patients with homozygous familial hypercholesterolemia, the recommended dose is 10/40 mg daily administered in the evening.

Precautions

This medication is primarily used to lower blood cholesterol levels. Caution should be exercised as muscle problems may arise while taking this medication. If muscle pain or weakness occurs, notify a doctor immediately. Patients with liver function problems or persistent unexplained increases in liver enzyme levels should not take this medication. Women who are pregnant or breastfeeding should not use this medication, and women of childbearing potential must confirm their pregnancy status before taking it. The risk of muscle problems or side effects may increase when this medication is taken with certain other drugs, so be sure to inform your doctor or pharmacist of any other medications you are taking. Elderly patients or those with decreased kidney function need to exercise greater caution when using this medication. Rarely, various side effects such as skin rashes, liver function abnormalities, gastrointestinal symptoms, headaches, dizziness, etc. may occur, and if symptoms persist or worsen, consult medical personnel. It is advisable to regularly monitor liver function and muscle status through blood tests while taking this medication. Additionally, this medication may not be suitable for patients with certain genetic disorders, thus the individual's health status should be thoroughly considered when using it.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blisters, skin peeling, pain in oral and eye mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, liver abnormalities, sudden and severe

Mild side effects

  • Headache
  • diarrhea
  • influenza
  • upper respiratory infection
  • muscle pain
  • limb pain
  • fatigue
  • abdominal pain
  • nausea
  • constipation
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  • dyspepsia
  • mucous stools
  • irritable bowel syndrome
  • sore throat
  • nocturia
  • hematuria
  • itching
  • weight loss
  • facial swelling
  • thirst
  • weakness
  • sensory loss
  • insomnia
  • dizziness
  • paresthesia
  • depression
  • cholecystitis
  • alopecia
  • skin dryness
  • changes in hair and nails
  • flat warts drug rash
  • gynecomastia
  • decreased libido

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a sealed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to ensure the drug's efficacy is preserved and prevent deterioration.

Appearance and packaging

Appearance

White to pale yellow, biconvex, rectangular tablets

Package unit

30 tablets (10 tablets/PTP x 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.