Subast Tablet 20 Milligrams (Rosuvastatin Calcium)

Adult dose

This can be taken at any time of the day, regardless of meals. The initial dose is 5 milligrams once daily, and the maintenance dose is 10 milligrams once daily. The maintenance dose can be adjusted every 4 weeks or longer based on LDL cholesterol levels, treatment goals, and the patient’s response, and can be increased to a maximum of 20 milligrams daily.

Child dose

For pediatric patients aged 10 to 17 years, the dosage can be 5 milligrams to 20 milligrams once daily. The dosage should be adjusted individually according to the treatment goals, with adjustments made at intervals of 4 weeks or longer.

This medication should not be administered to certain patients. For example, it must not be used in patients who have allergies to any of its components, those with severely impaired liver function, patients with muscle diseases, and those with severely impaired kidney function. Women who are pregnant or nursing, as well as women of childbearing age who are not using appropriate contraception, must consult a physician before using this medication, and potential risks to the fetus must be adequately considered. Patients at high risk for muscle-related side effects, such as those with moderate or severe kidney impairment, hypothyroidism, a family history of muscle diseases, or those taking certain medications, should avoid high doses of this medication. Additionally, this medication contains lactose, so patients with lactose intolerance should not use it. Patients with poor liver function or those consuming excessive alcohol should undergo regular liver function tests while using this medication, and patients with hypercholesterolemia due to hypothyroidism or nephrotic syndrome should start this medication after treating the underlying condition. If symptoms like muscle pain, weakness, or cramps occur, they should inform a doctor immediately, and blood tests should be conducted to check for muscle damage. If symptoms are severe or blood test results are unfavorable, discontinuation of the medication may be necessary. Rarely, severe skin reactions, liver damage, neurological abnormalities, or muscle rupture may occur with this medication, so patients should consult medical personnel immediately if any unusual symptoms arise. This medication may interact with other drugs, so patients taking other medications should inform their doctor or pharmacist, especially if taking certain antivirals, immunosuppressants, or fibrate medications. Pregnant or nursing women should not use this medication, and women of childbearing age should use appropriate contraceptive methods. In cases of overdose, there is no specific antidote, and treatment should be symptomatic, with regular monitoring of liver function and muscle enzyme levels. Dizziness may occur while taking this medication, so patients should exercise caution when driving or operating machinery.

Serious side effects

Allergic reactions including hives and angioedema, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, ocular muscle weakness, rhabdomyolysis, immune-mediated necrotizing myopathy, polyneuropathy, Stevens-Johnson syndrome, acute kidney failure, oliguria, severe edema, increased blood pressure, thrombocytopenia

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• diarrhea

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature. Doing so will help ensure the medication's effectiveness is safely maintained for a long period of time.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/box [15 tablets/PTP/X2], 300 tablets/bottle