Colduet Tablet 5mg/10mg

Adult dose

This medication is administered only to adults, and the dosage should be individualized for each patient based on the efficacy and tolerability of each component, amlodipine/atorvastatin. Amlodipine (Esamodipine): 5 (2.5) mg should be taken orally once daily, and the dose may be increased to a maximum of 10 (5) mg once daily depending on the patient's response. Atorvastatin: Recommended for patients with primary hypercholesterolemia and mixed dyslipidemia.

This medication should not be used in certain patients. For example, patients with allergies to this drug or similar classes of drugs, those with severe liver dysfunction, pregnant or breastfeeding women, patients with muscle disorders, severe aortic stenosis patients, patients in shock, those who recently experienced a myocardial infarction, patients with unstable angina, and patients taking certain antivirals should not take this medication. Additionally, patients with severely impaired kidney function, elderly individuals, alcoholics, patients with a history of liver disease, and those at risk for muscle damage should use this medication with caution. These patients should have muscle enzyme levels monitored before and during treatment and their condition closely observed. Taking this medication can lead to low blood pressure, dizziness, headaches, swelling, and musculoskeletal pain. Rarely, liver function abnormalities or serious allergic reactions, and muscle damage can occur, so any symptoms should be reported to a doctor immediately. Pregnant women should not take this medication as it may pose risks to the fetus, and women of childbearing age should practice adequate contraception while taking it. Breastfeeding women are also advised not to take this medication. This medication has many drug interactions, so patients taking other medications must inform their doctor or pharmacist, especially when taking certain antibiotics, antifungals, immunosuppressants, some antihypertensives, and anticoagulants. Overdosing on this medication may present severe hypotension, shock, and cardiac dysfunction, necessitating an immediate visit to a medical facility where treatment will depend on the symptoms. The safety of this medication for children and elderly patients has not been adequately confirmed, thus requiring special attention. Finally, this medication should be stored out of reach of children, and the container should not be replaced. It is recommended to avoid taking it with grapefruit juice as it may alter the medication's effectiveness.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle