Zocor 20 mg (Simvastatin)

Adult dose

Administer 5 to 40 mg once daily in the evening. The initial starting dose is 40 mg per day, and patients with mild to moderate hypercholesterolemia may start at 10 mg. Dosage adjustments may be necessary based on specific patient groups, and it can be given up to a maximum of 80 mg. For patients with renal impairment, start at 5 mg per day in severe cases.

Child dose

For pediatric patients aged 10 to 17 years, initiate with 10 mg once daily in the evening, with adjustments up to a maximum of 40 mg. When adjusting the dosage, space the intervals by more than 4 weeks.

This medication may cause muscle-related issues such as myopathy and rhabdomyolysis, so caution is especially necessary when taken in high doses. You should not use this medication if you have a history of allergic reactions, liver disease, are pregnant or breastfeeding, or are currently taking certain medications. Patients with poor liver function, alcoholism, kidney impairment, hypothyroidism, hereditary muscle disorders, the elderly, and women should use this medication with caution. If you experience unusual symptoms such as muscle pain, muscle weakness, or muscle tenderness while taking this medication, you should immediately inform your doctor, and discontinue the medication if severe. Regular liver function tests are important since this medication can affect liver function; and if symptoms of hepatitis or jaundice appear, you should stop taking the medication immediately. This medication may interact with multiple drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Particularly, if taken alongside certain antifungals, antibiotics, immunosuppressants, calcium channel blockers, the risk of muscle problems may increase, so caution is needed. Women who may become pregnant must use contraception while taking this medication, and should discontinue it immediately if pregnancy is confirmed. For children and adolescents, this medication is restricted for use only in patients aged 10 or older, specifically between the ages of 10 and 17, as it may affect growth and sexual maturity, thus requiring expert management. Elderly patients may have higher blood concentrations of this medication, increasing the risk of side effects, so caution is advised. Avoid consuming specific foods, such as grapefruit juice, while taking this medication, and visit a medical institution immediately in case of an overdose. When stored, keep it out of reach of children and in its original container to maintain quality.

Serious side effects

Hives, severe swelling, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with fever, blisters, peeling skin, oral/ocular mucosa pain, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, skin or eye jaundice, profound lethargy, liver dysfunction (jaundice), sudden and severe headache, lightning-like headache

Mild side effects

• Abdominal pain
• weakness
• constipation
• diarrhea
• indigestion
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This medication should be stored in a tightly closed container as it may be sensitive to air and moisture. It is also important to keep it at room temperature below 30 degrees Celsius to maintain its effectiveness.

Appearance

Brownish-yellow, oval film-coated tablets engraved with MSD 740 on one side

Package unit

30 tablets (15 tablets/PTP x 2 PTP), 300 tablets (300 tablets/bottle)