Duo-Dainjeong

Adult dose

For children aged 12 and older and adults: The dosage is adjusted according to the degree of pain and therapeutic response. The initial recommended dose is 2 tablets, thereafter the dosing interval should be at least 6 hours, not exceeding 8 tablets per day. The lowest effective dose should be administered for the shortest duration possible. Ensure that this medication is not used for longer than necessary, and in cases where prolonged use is required due to the nature or severity of the condition, regular monitoring should be conducted to determine the need for continued administration of this medication. Elderly Administer the standard adult dosage. However, in elderly patients over 75 years of age, the elimination half-life of tramadol is increased by 17% when administered orally, therefore, the medication should be given at intervals of at least 6 hours. Patients with renal failure In moderately impaired renal function (creatinine clearance of 10-30 mL/min), extend the dosing intervals to 12 hours. In patients with severe renal failure (creatinine clearance of less than 10 mL/min), the use of this medication is not recommended. Since tramadol is eliminated very slowly during hemodialysis and filtration, there is no need to readminister the medication after dialysis to maintain analgesic effect. Patients with liver failure For patients with moderate liver failure, carefully consider extending the dosing intervals. Do not administer this medication to patients with severe liver failure.

Child dose

For children aged 12 and older and adults: The dosage is adjusted according to the degree of pain and therapeutic response. The initial recommended dose is 2 tablets, thereafter the dosing interval should be at least 6 hours, with a maximum of

This medication may cause liver damage, so individuals who regularly consume more than three drinks a day must consult a doctor or pharmacist. If any abnormal reactions such as rash or itching occur during the use of this medication, stop taking it immediately and inform a doctor. There is a risk of seizure; therefore, this medication should be used cautiously in individuals with a history of seizures or those taking other medications that can trigger seizures. Severe allergic reactions that can be life-threatening can occur very rarely while taking this medication, so any unusual symptoms should be discussed immediately with medical staff. Patients with acute and severe asthma may have difficulty breathing when taking this medication, so treatment must be conducted in a facility with medical personnel present. Taking this medication together with alcohol or central nervous system depressants like sedatives can lead to severe drowsiness or respiratory depression, so caution is needed in combination. Patients with head injuries or elevated intracranial pressure must consult a doctor, as this medication may increase brain pressure. This medication can lead to dependence; therefore, dosing duration and amount should be adjusted according to a professional's guidance for long-term use. Patients with impaired liver function or liver disease must consult a doctor before taking this medication, and must not exceed the recommended dosage. Those who genetically metabolize this medication quickly are at increased risk for respiratory depression and must exercise caution. Children under 12 years of age and teenagers under 18 who have undergone tonsillectomy or adenoidectomy should not take this medication. This medication can cause sleep apnea and hypoxemia, so regular monitoring of symptom exacerbation is required, and dosage should be adjusted if necessary. Elderly patients or those with decreased kidney function should be closely monitored for adverse reactions while taking this medication. Women who are pregnant or may become pregnant must consult a doctor before taking this medication, and nursing mothers should avoid it if possible. This medication can cause drowsiness or dizziness, so caution is needed when driving or operating machinery. Overdosing can result in severe respiratory depression, seizures, liver damage, etc., so the dosage must be strictly adhered to, and immediate emergency treatment must be obtained in case of overdose. This medication may interact with other drugs, so any other medications being taken should be disclosed to medical personnel. It should be stored in a safe place out of reach of children, with careful management to prevent drug misuse.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities coupled with cough + fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Loss of appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a sealed container to prevent air or moisture from entering, ideally at room temperature below 25 degrees Celsius. Storing it this way helps maintain the medication's effectiveness for a longer time.

Appearance

Pale yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle