Uptraset Semi Tablet

Adult dose

Children aged 12 and older and adults: The dosage should be adjusted according to the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and subsequent doses should be at least 6 hours apart, but not exceeding 16 tablets per day. The lowest effective dose should be administered for the shortest duration necessary. Avoid prolonged use of this medication beyond what is required, and if long-term treatment is needed due to the nature and severity of the condition, regular monitoring should be carried out to assess the continuous use of this medication. Elderly Administer the usual adult dosage, but for elderly patients aged 75 and older, when taking tramadol orally, the half-life of tramadol can increase by 17%, thus doses should be spaced at least 6 hours apart. Patients with renal impairment For patients with moderate renal impairment (creatinine clearance of 10-30 mL/min), extend the dosing interval to 12 hours. For patients with severe renal impairment (creatinine clearance below 10 mL/min), use of this medication is not recommended. Tramadol is removed very slowly during dialysis and filtration, so there is no need to re-administer the medication after dialysis to maintain analgesic effects. Patients with hepatic impairment For patients with moderate hepatic impairment, carefully consider extending the dosing interval. This medication should not be administered to patients with severe hepatic impairment.

Child dose

Children aged 12 and older and adults: The dosage should be adjusted according to the patient's level of pain and treatment response. A starting dose of 4 tablets is recommended, and subsequent doses should be at least 6 hours apart, but not exceeding 16 tablets per day.

This medication may put a burden on the liver, so individuals who consume more than a certain amount of alcohol daily must consult a doctor or pharmacist before taking it. If you experience severe rashes or itching on the skin while taking this medication, stop taking it immediately and seek medical attention. One of the active ingredients in this medication, tramadol, may increase the risk of seizures, so patients with a history of seizures or at high risk for seizures should use it cautiously. This medication may rarely cause severe allergic reactions and can pose life-threatening risks to patients with acute asthma, so special caution is necessary. Taking this medication with central nervous system depressants or alcohol can cause drowsiness, respiratory depression, or coma, so it should be avoided or used with caution. Patients with head injuries or brain diseases may see an exacerbation of breathing problems while taking this medication, so they should consult their doctor. This medication can lead to dependency similar to that of narcotic analgesics, so caution is necessary regarding the risk of dependency and abuse with long-term use. Patients with impaired liver function must consult with healthcare professionals before taking this medication and should not exceed the recommended dosage due to the risk of liver damage. Patients with certain genotypes may have accelerated metabolism of this medication, leading to serious side effects like respiratory depression, so dosage adjustments or alternative medications should be considered in such cases. This medication should not be administered to children under 12 years old or teenagers under 18 years old who have undergone tonsillectomy and adenoidectomy. This medication may cause sleep apnea or hypoxemia, so patients should be monitored periodically for any symptoms or worsening conditions. Drowsiness or dizziness may occur during treatment, and caution is needed when driving or operating machinery or performing other hazardous tasks. Overdose may result in severe respiratory depression, seizures, or liver damage, so adherence to the prescribed dosage is critical, and immediate emergency treatment should be sought if overdose is suspected. This medication should be kept out of the reach of children, and it is essential to store it safely to prevent misuse and abuse.

Serious side effects

Hives, severe swelling (edema), breathing difficulties, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis, hepatitis, liver abnormalities (jaundice), seizures, confusion, stupor, vision abnormalities, paralysis, thunderclap headache, loss of consciousness, myocardial infarction, hypotension, urinary abnormalities, severe edema, asthma, breathing difficulties, respiratory depression, life-threatening respiratory depression, acute generalized exanthematous pustulosis, acute generalized exanthematous pustular dermatitis

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air or moisture exposure and kept in a cool place at or below room temperature (25 degrees Celsius). This will help maintain the medication’s effectiveness and safety.

Appearance

Pale yellow, rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle