Diwaren Tablet

Adult dose

For the initial dose, it is recommended to administer 2 tablets, and thereafter maintain an interval of at least 6 hours, not exceeding 8 tablets per day. Administer the lowest effective dose for the shortest period possible. Elderly patients should generally be given the usual adult dose, but in patients aged 75 and older, maintain a minimum interval of 6 hours. For moderate renal impairment patients, extend the dosing interval to 12 hours, and for severe renal impairment patients and

Child dose

For children aged 12 and above, apply the same dosage as adults.

This medication can cause liver damage in individuals who regularly consume more than three glasses of alcohol a day; therefore, it must be discussed with a doctor or pharmacist. One of the components of this drug, acetaminophen, can rarely cause serious skin reactions; if a rash or hypersensitivity reaction occurs, stop taking it immediately and inform medical personnel. Tramadol included in this medication may increase the risk of seizures if taken in doses exceeding the recommended amount; the risk may further increase when taken with specific antidepressants or narcotic analgesics. Moreover, tramadol can rarely cause fatal allergic reactions, so if such symptoms appear, consult medical personnel immediately. For patients with acute and severe bronchial asthma, this medication may suppress breathing, so it should only be administered in an environment monitored by healthcare professionals. Co-administration with alcohol or central nervous system depressants like benzodiazepines can result in severe drowsiness, respiratory depression, coma, or even death, and should be avoided. Caution is needed when prescribing this medication to patients with increased intracranial pressure or head injuries, as respiratory depression may exacerbate brain pressure. Tramadol has the potential to cause dependence similar to that of morphine, thus monitoring for dependency is required with long-term use. The acetaminophen component can cause liver damage in overdose situations, so care should be taken that the total daily dosage does not exceed 4,000mg; patients with poor liver function should consult a doctor before taking it. Patients with a genetic trait of ultra-rapid CYP2D6 metabolism may produce excessive active metabolites, which may present a serious risk of respiratory depression; consultation with medical personnel is required before use. This medication should not be administered to children under 12 years of age or adolescents under 18 after certain surgeries, especially those with sleep apnea due to a risk of respiratory depression. This medication can cause or worsen sleep apnea and hypoxemia, and dosage adjustments or discontinuation should be considered if such symptoms occur or worsen. Elderly patients or those at risk of hyponatremia should monitor symptoms of hyponatremia during the use of this medication. This drug should not be given to patients with allergies to certain components, central nervous system drug addiction, severe respiratory depression, head injuries, those on MAO inhibitors, etc. While taking this medication, it is important not to exceed the recommended dosage and not to take other tramadol or acetaminophen preparations concurrently. Discontinuing this medication abruptly may result in withdrawal symptoms, so the dose should be gradually reduced as directed by a physician. Interactions may occur if combined with certain antidepressants, narcotic analgesics, central nervous system depressants, warfarin, etc., so it is crucial to inform medical personnel before use and monitor carefully. Driving or operating machinery can result in drowsiness or dizziness due to this medication, so caution is advised. In case of overdose, serious side effects such as respiratory depression, seizures, or liver damage can occur, necessitating immediate medical attention. Women who are pregnant or breastfeeding should carefully administer this medication, as it may pose risks to the fetus or newborn after consulting with medical personnel. This medication should be stored out of reach of children to prevent accidental ingestion or misuse.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, oral/ocular mucosa pain, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, altered consciousness, visual disturbances, paralysis, decreased urine output

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, away from direct sunlight, and at a cool room temperature, specifically below 25 degrees Celsius.

Appearance

Light yellow rectangular film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle