Medication info
Tramifen Tablets

Tramifen Tablets

Prescription medicationTablet경구
Ingredient · strength
Tramadol Hydrochloride›37.5mg / 1 tabletAcetaminophen›325mg / 1 tablet
Manufacturer / importer
하나제약(주)
Appearance
Pale yellow, oblong film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200711886 · Notified 2007.10.29 · Insurance code 657802020

Summary

Main use
Relief of moderate to severe acute and chronic pain
Who takes it
Adults · Children
Adult dose
The initial recommended dosage is 2 tablets, followed by a minimum interval of 6 hours between doses, not to exceed 8 tablets per day. Administer the lowest effective dose for the shortest duration possible. For elderly patients, the standard adult dosage is administered, but for those aged 75 and above, a minimum interval of 6 hours should be maintained between doses. For moderate renal impairment, extend the dosing interval to every 12 hours. Severe renal impairment and severe
Child dose
Children over 12 years of age should be administered the same dosage as adults.

Ingredients

Manufacturer
하나제약(주)

Efficacy & effects

Relief of moderate to severe acute and chronic pain

  • Acute pain
  • chronic pain
View approved original text

This medication is used to effectively relieve acute and chronic pain ranging from moderate to severe.

How to take

Adult dose

The initial recommended dosage is 2 tablets, followed by a minimum interval of 6 hours between doses, not to exceed 8 tablets per day. Administer the lowest effective dose for the shortest duration possible. For elderly patients, the standard adult dosage is administered, but for those aged 75 and above, a minimum interval of 6 hours should be maintained between doses. For moderate renal impairment, extend the dosing interval to every 12 hours. Severe renal impairment and severe

Child dose

Children over 12 years of age should be administered the same dosage as adults.

Precautions

This medication may put a strain on the liver, so anyone who drinks more than three alcoholic beverages daily should consult a doctor or pharmacist before use. If any skin rashes or other allergic reactions occur while taking this medication, you should immediately stop taking it and seek medical attention. Tramadol, the main ingredient in this medication, may cause seizures, so patients with a history of seizures or those at high risk for seizures should use it with caution. Particularly, taking this medication with certain antidepressants or other narcotic analgesics may increase the risk of seizures, so caution is advised. In patients with severe asthma, administering this medication may lead to difficulty in breathing, so it should only be used in a medically equipped setting. There is a risk of severe drowsiness, respiratory depression, and coma if this medication is taken together with central nervous system depressants or alcohol, so either avoid concurrent use or exercise extreme caution. Patients with head injuries or elevated intracranial pressure may experience worsening symptoms while taking this medication, so caution is needed. This medication may cause psychological or physical dependence; therefore, it should be taken according to a doctor's guidance for prolonged use. Patients with compromised liver function may be at risk for liver damage due to one of the components of this medication, acetaminophen, so they must consult a doctor. This medication should not be used in children, especially those under 12 years of age or adolescents aged under 18 who have undergone tonsillectomy. This medication may worsen sleep apnea or hypoxia, so patients with symptoms should be closely monitored while taking it. Elderly patients may have a risk of decreased liver, kidney, and heart function, so increased caution is necessary when taking it. Women who are pregnant or of childbearing potential should use this medication cautiously after consultation with a doctor, as it may affect the fetus. Breastfeeding women should avoid using this medication as it may transfer to breast milk and affect the baby. This medication may cause drowsiness or dizziness, so caution is required when driving or operating machinery. In case of overdose, severe respiratory depression, seizures, liver damage, etc., can occur, so the prescribed dosage must be strictly followed. Drug interactions may occur while taking this medication, so if other medications are being taken, it is essential to inform the doctor or pharmacist. This medication should be stored out of the reach of children, and caution should be exercised to prevent misuse or abuse.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, lightning headache, seizure, confusion, visual disturbances, paralysis, urinary retention

Mild side effects

  • Decreased appetite
  • insomnia
  • depression
  • dizziness
  • headache
  • drowsiness
  • nausea
  • vomiting
  • constipation
  • dry mouth
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  • diarrhea
  • dyspepsia
  • abdominal pain
  • abdominal discomfort
  • flatulence
  • pruritus
  • sweating
  • rash
  • fatigue
  • flushing
  • hypoglycemia
  • anxiety
  • nervousness
  • emotional instability
  • euphoria
  • decreased libido
  • sleep disturbance
  • confusion
  • disorientation
  • agitation
  • abnormal dreams
  • drug abuse
  • hallucinations
  • withdrawal syndrome
  • migraine
  • somnolence
  • sensory impairment
  • tremors
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air exposure and is best kept at room temperature between 1°C to 30°C. This storage method helps maintain the medication's effectiveness and prevents degradation.

Appearance and packaging

Appearance

Pale yellow, oblong film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.