Medication info
Loaderplus Tablet

Loaderplus Tablet

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›50mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
위더스제약(주)
Appearance
Yellow oval film-coated tablet
Packaging
30 tablets / bottle, 100 tablets / bottle
Approval status
Active

MFDS item code 200608192 · Notified 2006.08.31 · Insurance code 660700340

Summary

Main use
Improvement of blood pressure control when monotherapy is inadequate for hypertension
Who takes it
Adults · Children
Adult dose
Start with Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily. If blood pressure is not controlled after 3 weeks of treatment, the dosage may be increased to a maximum of Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg once daily. For patients with kidney impairment and creatinine clearance of 30 mL/min or more, the regular dosage should be administered. Administration is not recommended for patients with liver impairment.
Child dose
There is no experience using this medication in children and adolescents (under 18 years), and it should not be administered.

Ingredients

Manufacturer
위더스제약(주)

Efficacy & effects

Improvement of blood pressure control when monotherapy is inadequate for hypertension

  • Hypertension
View approved original text

This medication is used to effectively control blood pressure in patients with hypertension whose blood pressure is not sufficiently controlled with monotherapy.

How to take

Adult dose

Start with Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily. If blood pressure is not controlled after 3 weeks of treatment, the dosage may be increased to a maximum of Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg once daily. For patients with kidney impairment and creatinine clearance of 30 mL/min or more, the regular dosage should be administered. Administration is not recommended for patients with liver impairment.

Child dose

There is no experience using this medication in children and adolescents (under 18 years), and it should not be administered.

Precautions

This medication can cause serious harm to the fetus and newborn, especially during pregnancy, so use should be discontinued immediately upon confirmation of pregnancy. Patients with allergies to any of the ingredients in this medication or severe impairment of kidney or liver function should not take it. Patients with a history of hypotension, electrolyte imbalance, kidney disease, liver disease, diabetes, gout, etc. need to take special caution when using this medication. During treatment, blood pressure, kidney function, and electrolyte levels should be monitored regularly to detect any abnormal signs early. This medication can alter serum potassium levels, so it is important to avoid taking potassium supplements or drugs containing potassium simultaneously. Due to the hydrochlorothiazide component, the skin may become sensitive to sunlight, so prolonged sun exposure should be avoided, and appropriate UV protection measures should be taken as needed. Symptoms such as dizziness or drowsiness may occur, so caution is required when driving or operating machinery. Overdose may lead to hypotension or heart abnormalities, so it is essential to adhere to the prescribed dosage and amount. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before deciding to take this medication. Special caution is needed if breastfeeding, as this medication may cause adverse reactions in the infant. Safety and efficacy have not been established for children or adolescents, so it should not be administered to them. This medication should be stored in its original container and kept out of reach of children, as transferring it to another container may pose a risk of misuse or degradation in quality.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema (swelling of lips and eyelids with facial rash), skin peeling, hemolysis, difficulty breathing, yellowing of the skin or eyes (jaundice), acute respiratory distress syndrome (ARDS), angioedema (laryngeal or glottal swelling that may cause airway obstruction, swelling of face/lips/pharynx/tongue), vasculitis (including Henoch-Schönlein purpura), anaphylaxis, hepatitis, enteritis

Mild side effects

Abdominal pain, swelling/edema, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, chest pain, facial edema, fever, orthostatic hypotension, fainting, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, second-degree atrioventricular block, anorexia, constipation, toothache, dry mouth, dyspepsia, flatulence, gastritis, vomiting

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a dark container. It is best to keep the temperature between 1 degree and 30 degrees Celsius at room temperature to maintain its effectiveness and ensure safe use.

Appearance and packaging

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets / bottle, 100 tablets / bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.