Septpezil 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, administered as 5 mg once daily before bedtime. For the first 4–6 weeks, the dosage should be maintained at 5 mg. After assessing the clinical response during this period, the dosage may be increased up to 10 mg. When increasing to 10 mg daily, care should be taken regarding gastrointestinal adverse reactions.

Child dose

There is no experience using this medication in children.

This medicine should not be used by patients with allergies to certain ingredients or by women who are pregnant or breastfeeding. Patients with genetic lactose intolerance or lactose enzyme deficiency should also be cautious. Patients with heart conditions or issues with heart rhythm should use this medicine carefully, as bradycardia or arrhythmia can occur. Those with a history of peptic ulcers or who are taking non-steroidal anti-inflammatory drugs should be cautious as gastrointestinal issues may arise. Patients with asthma or obstructive pulmonary disease may experience worsening symptoms due to bronchial constriction or increased mucus secretion. Patients with extrapyramidal disorders such as Parkinson's disease should also be cautious, as symptoms may worsen with the use of this medication. Individuals with allergies to the color additives included in this medicine should use it carefully. Possible side effects include heart-related issues, gastrointestinal bleeding, liver function abnormalities, seizures, movement disorders, and respiratory difficulties; if any abnormal symptoms occur, consult a doctor immediately. This medication may affect driving or operation of machinery, so caution is advised, especially during the initial dosing or when changing doses. There may be interactions with other medications, so it is essential to inform healthcare providers of any other medications being taken. Pregnant or breastfeeding women should avoid using this medication, and if necessary, should consult a specialist before use. Safety for pediatric use has not been established, so it should not be used in children. In cases of overdose, severe symptoms such as nausea, vomiting, bradycardia, hypotension, and respiratory depression may occur, so dosing must be strictly adhered to and medical attention sought immediately in case of overdose. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

Nausea, vomiting, loss of appetite, diarrhea, dizziness, insomnia, drowsiness, headache, fatigue, muscle pain, rash, itching, sweating, increased blood pressure, decreased blood pressure, palpitations, anxiety, hallucinations, somnolence, confusion, nervousness, delusions, hyperactivity, increased libido, hypersexuality, tremors, gait disturbances, involuntary movements, decreased concentration, mental dullness, insomnia, blood disorders (anemia, leukopenia, thrombocytopenia, etc.), urinary incontinence, empty

This medication should be stored in a tightly sealed container to prevent air ingress and kept at room temperature between 1°C and 30°C. Proper storage will help maintain the medication’s effectiveness for a longer period.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle