NutriFlex Peri 40 Injection

Adult dosage

As total amino acids, the maximum dosage is 1-1.5 g per kg of body weight per day, and the infusion rate should be a concentration of about 10 g of total amino acids over 60 minutes. The infusion rate should be dripped at 25-30 drops per minute. This medication is generally administered intravenously into the peripheral veins.

Children's dosage

In children, dosage and infusion rate should be adjusted appropriately.

This medication must be used strictly according to a doctor's instructions. When used with intravenous calcium-containing preparations, precipitates may form if mixed with ceftriaxone, so the same infusion device should not be used simultaneously. This should not be administered to patients with progressive liver disease, severe kidney disorders, metabolic disorders, wasting cardiac disease, pulmonary edema, anuria, hypernatremia, heart block, myasthenia gravis, metabolic acidosis, diabetic complications excluding hypoglycemia, untreated nephrogenic diabetes insipidus, patients on high-dose cardiac glycoside treatment, infants, patients with excessive water supply, and patients with hyperkalemia. It should be administered cautiously to patients with congestive heart failure, severe renal failure, liver impairment, pancreatic disorders, severe burns, diabetes mellitus, diabetes insipidus, dehydration, and obstructive uropathy. During administration, abnormal reactions such as acidosis, hypersensitivity, nausea, vomiting, palpitations, increased blood pressure may occur, so close monitoring is required. In cases of rapid large-volume administration, acidosis and hypernitrogenemia may occur, making slow administration essential. This medication has a high osmolarity, which may cause osmotic diuresis, so caution should be taken against excessive dosing. Diabetic patients should frequently check blood glucose levels, and patients with liver or kidney disease should have liver and kidney function checked regularly during administration. There may be interactions when used with other medications, especially tetracyclines, calcium salts, potassium-sparing diuretics, and ACE inhibitors, so caution is advised. Safety has not been established during pregnancy, so it should only be administered when the therapeutic benefits outweigh the risks. It is advisable not to use in infants, and specifically formulated amino acid products should be recommended for children. Elderly patients have decreased physiological function, so administration speed should be slow and dosage adjusted accordingly. In case of overdose, symptoms such as dizziness, nausea, osmotic diuresis may occur, and in severe cases, administration should be stopped, and peritoneal dialysis or hemodialysis should be carried out if necessary. This medication must be prepared and managed in a sterile manner, and the container should be checked for damage and clarity before use. The mixed solution is stable for 24 to 28 hours, so it should be used within that period and any remaining medication should not be reused. Storage should be maintained in its original packaging away from light at room temperature, and expired medication should not be used.

Serious side effects

Severe allergic reactions (hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness), severe skin reactions (severe rash with fever, blisters, skin peeling, pain of oral/ocular mucosa), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever), liver dysfunction (jaundice) (yellowing of the skin or eyes (jaundice), profound lassitude), severe neurological symptoms.

Mild side effects

• Rarely
• rashes
• nausea
• vomiting
• chest discomfort
• palpitations
• tachycardia
• increased blood pressure
• chills
• fever

This medication should be stored in a sealed container to avoid exposure to air and light. Additionally, it should be kept in a cool place between 15 to 25 degrees Celsius to maintain its efficacy.

Appearance

A clear solution filled in a transparent plastic container with a pale yellow (A solution, B solution) liquid

Package unit

Bag - 1000 milliliters/Bag