Atenolol (Anoljeong)

Adult dose

1. Hypertension: For adults, the initial dose of atenolol is 50mg once daily, either alone or in combination with diuretics (thiazide). If no effects are observed within 1-2 weeks, increase the dose to 100mg once daily, not exceeding 100mg per day. 2. Angina: Administer 100mg once daily in 1-2 divided doses, not exceeding 100mg per day. 3. Patients with renal impairment: Creatinine clearance 15-35 mL/min: dose 50mg once daily; <15 mL/min: 25mg once daily or 50mg every two days. Dosage may be adjusted appropriately based on age and symptoms.

This medicine should not be used in patients who are allergic to the main active ingredient or additives. Patients with severe bronchial asthma or chronic obstructive pulmonary disease should not take this medicine. It is contraindicated in patients with diabetic ketoacidosis or metabolic acidosis. Patients with severe bradycardia or certain heart conduction disorders should also avoid using this medicine. This medicine should not be administered to patients with cardiogenic shock or right heart failure due to pulmonary hypertension, or congestive heart failure. Patients with severe hypotension or peripheral circulation disorders may face risks if taking this drug. Careful monitoring is needed in patients with hyperthyroidism as it may lead to thyroid storm. This medicine should not be used in untreated pheochromocytoma patients. Patients with bronchial asthma or a risk of bronchospasm should be given this medicine with careful observation. Patients at risk of developing heart failure should be monitored regularly and may need to take appropriate medications in combination. Diabetic patients or patients with hypoglycemia may display hypoglycemic symptoms that can be masked, thus blood sugar levels should be monitored closely. Patients with significantly impaired liver or kidney function may require dosage adjustment or careful administration. Elderly patients should begin with a low dosage and observe their physical condition closely during treatment. This medicine can cause various side effects. If allergic reactions such as skin rash or itching occur, discontinue use immediately. Symptoms such as reduced tear production, vision disturbances, or dry eyes should be reported to a doctor if they arise. Be cautious as symptoms like slowed heart rate, low blood pressure, and cold extremities can develop. Mental confusion, insomnia, dizziness, and headaches can also manifest as neurological side effects. Gastrointestinal side effects such as digestive disturbances, nausea, vomiting, diarrhea, and constipation have been reported. Respiratory difficulties, wheezing, or bronchospasm may occur; therefore, patients with respiratory diseases must be particularly cautious. Liver dysfunction or renal impairment may rarely occur, necessitating regular testing. There may also be side effects such as hair loss, skin disorders, blood abnormalities, and erectile dysfunction. If this medicine is taken for a prolonged period, regular checks of cardiac function, blood pressure, and pulse are required. Abruptly stopping the medication can worsen symptoms, so the dosage should be gradually reduced under medical supervision. Patients scheduled for surgery must stop taking this medicine 24 hours before the procedure, and caution is needed during anesthesia as well. Mild dizziness may occur when starting treatment, so driving or operating hazardous machinery should be avoided. This medicine is excreted through the kidneys; thus, dosage adjustments are needed in patients with reduced kidney function. When taken with other sympatholytics, insulin, or calcium channel blockers, the risk of side effects may increase due to interactions; therefore, consulting a doctor is essential. Pregnant or nursing women should exercise caution when taking this medicine as it may affect the fetus or newborn. Safety in pediatric patients has not been sufficiently established, thus extra caution is needed when prescribing to children. In case of overdose, symptoms may include decreased heart rate, hypotension, bronchospasm, and hypoglycemia; immediate medical attention should be sought. This medication should be kept out of reach of children and stored away from high temperatures above 25 degrees Celsius.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, hypotension, atrioventricular block, sinoatrial block, asthma attack, respiratory distress, yellowing of the skin (jaundice), sudden and severe headache, headache, seizures, confusion, visual disturbances, paralysis, markedly reduced urine output, generalized severe swelling, swelling accompanied by elevated blood pressure.

Mild side effects

• Rash
• itching
• decreased tear production
• blurred vision
• dry eyes
• bradycardia
• cold extremities
• palpitations
• increased heart size
• chest tightness

This medicine may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is advisable to keep the storage temperature between 1 degree and 30 degrees Celsius. Avoid storage in excessively hot or cold locations.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle